| Item Type | Name |
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Concept
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Oncogenes
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Concept
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Proto-Oncogene Proteins
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Concept
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Oncogene Proteins, Fusion
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Concept
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Oncogene Proteins v-myb
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Concept
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Proto-Oncogene Proteins c-pim-1
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Concept
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Proto-Oncogene Proteins c-kit
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Concept
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Proto-Oncogenes
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Concept
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Proto-Oncogene Proteins c-bcl-6
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Academic Article
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Analysis of the t(6;11)(q27;q23) in leukemia shows a consistent breakpoint in AF6 in three patients and in the ML-2 cell line.
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Academic Article
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Distribution of 11q23 breakpoints within the MLL breakpoint cluster region in de novo acute leukemia and in treatment-related acute myeloid leukemia: correlation with scaffold attachment regions and topoisomerase II consensus binding sites.
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Academic Article
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The human programmed cell death-2 (PDCD2) gene is a target of BCL6 repression: implications for a role of BCL6 in the down-regulation of apoptosis.
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Academic Article
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Chromatin-related properties of CBP fused to MLL generate a myelodysplastic-like syndrome that evolves into myeloid leukemia.
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Academic Article
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Retrovirus-mediated gene transfer of MLL-ELL transforms primary myeloid progenitors and causes acute myeloid leukemias in mice.
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Academic Article
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ELL and EAF1 are Cajal body components that are disrupted in MLL-ELL leukemia.
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Academic Article
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ELL-associated factor 2 (EAF2), a functional homolog of EAF1 with alternative ELL binding properties.
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Academic Article
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The elongation domain of ELL is dispensable but its ELL-associated factor 1 interaction domain is essential for MLL-ELL-induced leukemogenesis.
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Academic Article
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The human BCL6 transgene promotes the development of lymphomas in the mouse.
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Academic Article
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The elongation factor ELL (eleven-nineteen lysine-rich leukemia) is a selective coregulator for steroid receptor functions.
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Academic Article
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Repression of the PDCD2 gene by BCL6 and the implications for the pathogenesis of human B and T cell lymphomas.
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Academic Article
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Gene mutations, epigenetic dysregulation, and personalized therapy in myeloid neoplasia: are we there yet?
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Academic Article
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Cloning of ELL, a gene that fuses to MLL in a t(11;19)(q23;p13.1) in acute myeloid leukemia.
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Academic Article
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PDCD2, a protein whose expression is repressed by BCL6, induces apoptosis in human cells by activation of the caspase cascade.
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Academic Article
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PIM1 gene cooperates with human BCL6 gene to promote the development of lymphomas.
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Academic Article
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DNA rearrangements and altered transcripts of the MLL gene in a human T-ALL cell line Karpas 45 with a t(X;11) (q13;q23) translocation.
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Academic Article
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The human MLL gene: nucleotide sequence, homology to the Drosophila trx zinc-finger domain, and alternative splicing.
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Academic Article
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Detection of MLL gene rearrangements in adult acute lymphoblastic leukemia. A Cancer and Leukemia Group B study.
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Academic Article
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Abnormalities of chromosome band 11q23 and the MLL gene in pediatric myelomonocytic and monoblastic leukemias. Identification of the t(9;11) as an indicator of long survival.
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Academic Article
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Consistent deregulation of gene expression between human and murine MLL rearrangement leukemias.
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Academic Article
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Detection of 11q23/MLL rearrangements in infant leukemias with fluorescence in situ hybridization and molecular analysis.
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Academic Article
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EAF1, a novel ELL-associated factor that is delocalized by expression of the MLL-ELL fusion protein.
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Academic Article
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MLL fusion proteins preferentially regulate a subset of wild-type MLL target genes in the leukemic genome.
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Academic Article
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GFI1B, EVI5, MYB--additional genes that cooperate with the human BCL6 gene to promote the development of lymphomas.
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Academic Article
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Instructive Role of MLL-Fusion Proteins Revealed by a Model of t(4;11) Pro-B Acute Lymphoblastic Leukemia.
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Academic Article
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The full transforming capacity of MLL-Af4 is interlinked with lymphoid lineage commitment.
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Academic Article
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Quercetin Therapy for Selected Patients with PIM1 Kinase-Positive Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: A Pilot Study.
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Academic Article
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Cytokine-Regulated Phosphorylation and Activation of TET2 by JAK2 in Hematopoiesis.
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Academic Article
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Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia.
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Academic Article
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The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia.
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