| Item Type | Name |
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Concept
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Vasoconstriction
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Academic Article
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Differential distribution of electrophysiologically distinct myocytes in conduit and resistance arteries determines their response to nitric oxide and hypoxia.
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Academic Article
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Nebulized nitric oxide/nucleophile adduct reduces chronic pulmonary hypertension.
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Academic Article
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Diversity of response in vascular smooth muscle cells to changes in oxygen tension.
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Academic Article
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Acute hypoxic pulmonary vasoconstriction: a model of oxygen sensing.
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Academic Article
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Molecular identification of the role of voltage-gated K+ channels, Kv1.5 and Kv2.1, in hypoxic pulmonary vasoconstriction and control of resting membrane potential in rat pulmonary artery myocytes.
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Academic Article
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Pulmonary vasoconstriction, oxygen sensing, and the role of ion channels: Thomas A. Neff lecture.
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Academic Article
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Impairment of hypoxic pulmonary vasoconstriction in mice lacking the voltage-gated potassium channel Kv1.5.
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Academic Article
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Direct role for potassium channel inhibition in hypoxic pulmonary vasoconstriction.
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Academic Article
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O2 sensing is preserved in mice lacking the gp91 phox subunit of NADPH oxidase.
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Academic Article
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Molecular identification of O2 sensors and O2-sensitive potassium channels in the pulmonary circulation.
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Academic Article
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The mechanism(s) of hypoxic pulmonary vasoconstriction: potassium channels, redox O(2) sensors, and controversies.
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Academic Article
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Sildenafil reverses O2 constriction of the rabbit ductus arteriosus by inhibiting type 5 phosphodiesterase and activating BK(Ca) channels.
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Academic Article
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In vivo gene transfer of the O2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction in chronically hypoxic rats.
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Academic Article
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Cellular and molecular pathobiology of pulmonary arterial hypertension.
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Academic Article
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Hypoxic fetoplacental vasoconstriction in humans is mediated by potassium channel inhibition.
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Academic Article
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Acute oxygen-sensing mechanisms.
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Academic Article
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An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension.
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Academic Article
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The role of k+ channels in determining pulmonary vascular tone, oxygen sensing, cell proliferation, and apoptosis: implications in hypoxic pulmonary vasoconstriction and pulmonary arterial hypertension.
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Academic Article
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Potassium channel diversity in the pulmonary arteries and pulmonary veins: implications for regulation of the pulmonary vasculature in health and during pulmonary hypertension.
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Academic Article
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Hypoxic pulmonary vasoconstriction: redox regulation of O2-sensitive K+ channels by a mitochondrial O2-sensor in resistance artery smooth muscle cells.
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Academic Article
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Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic diversity in smooth muscle cells.
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Academic Article
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Oxygen-sensitive Kv channel gene transfer confers oxygen responsiveness to preterm rabbit and remodeled human ductus arteriosus: implications for infants with patent ductus arteriosus.
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Academic Article
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Blunted hypoxic pulmonary vasoconstriction in experimental neonatal chronic lung disease.
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Academic Article
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Oxygen activates the Rho/Rho-kinase pathway and induces RhoB and ROCK-1 expression in human and rabbit ductus arteriosus by increasing mitochondria-derived reactive oxygen species: a newly recognized mechanism for sustaining ductal constriction.
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Academic Article
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Counterpoint: Hypoxic pulmonary vasoconstriction is not mediated by increased production of reactive oxygen species.
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Academic Article
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The role of redox changes in oxygen sensing.
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Academic Article
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Developmental absence of the O2 sensitivity of L-type calcium channels in preterm ductus arteriosus smooth muscle cells impairs O2 constriction contributing to patent ductus arteriosus.
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Academic Article
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Hypoxic pulmonary vasoconstriction is unaltered by creatine depletion induced by dietary beta-guanidino propionic acid.
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Academic Article
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The effects of substance P on the preconstricted pulmonary vasculature of the anesthetized dog.
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Academic Article
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Hypoxic pulmonary vasoconstriction is enhanced by inhibition of the synthesis of an endothelium derived relaxing factor.
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Academic Article
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Increased endothelium-derived NO in hypertensive pulmonary circulation of chronically hypoxic rats.
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Academic Article
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Redox status in the control of pulmonary vascular tone.
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Academic Article
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Dithionite increases radical formation and decreases vasoconstriction in the lung. Evidence that dithionite does not mimic alveolar hypoxia.
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Academic Article
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Diphenyleneiodonium inhibits both potassium and calcium currents in isolated pulmonary artery smooth muscle cells.
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Academic Article
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Cellular and molecular basis of pulmonary arterial hypertension.
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Academic Article
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Simultaneous measurement of O2 radicals and pulmonary vascular reactivity in rat lung.
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Academic Article
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Anorexic agents aminorex, fenfluramine, and dexfenfluramine inhibit potassium current in rat pulmonary vascular smooth muscle and cause pulmonary vasoconstriction.
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Academic Article
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NG-monomethyl-L-arginine causes nitric oxide synthesis in isolated arterial rings: trouble in paradise.
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Academic Article
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The mechanism of acute hypoxic pulmonary vasoconstriction: the tale of two channels.
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Academic Article
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Potassium channels regulate tone in rat pulmonary veins.
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Academic Article
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Diversity in mitochondrial function explains differences in vascular oxygen sensing.
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Academic Article
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O2 sensing in the human ductus arteriosus: regulation of voltage-gated K+ channels in smooth muscle cells by a mitochondrial redox sensor.
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Academic Article
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Hypoxic pulmonary vasoconstriction.
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Academic Article
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Pergolide is an inhibitor of voltage-gated potassium channels, including Kv1.5, and causes pulmonary vasoconstriction.
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Academic Article
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Role of dynamin-related protein 1 (Drp1)-mediated mitochondrial fission in oxygen sensing and constriction of the ductus arteriosus.
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Academic Article
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Critical Genomic Networks and Vasoreactive Variants in Idiopathic Pulmonary Arterial Hypertension.
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Academic Article
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Hypoxic Pulmonary Vasoconstriction: From Molecular Mechanisms to Medicine.
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Academic Article
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Activation of the EGFR/p38/JNK pathway by mitochondrial-derived hydrogen peroxide contributes to oxygen-induced contraction of ductus arteriosus.
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Academic Article
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Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction.
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Academic Article
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Response by Dunham-Snary and Archer to Letter Regarding Article, "Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction".
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Academic Article
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Differentiating COVID-19 Pneumonia From Acute Respiratory Distress Syndrome and High Altitude Pulmonary Edema: Therapeutic Implications.
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Academic Article
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The molecular mechanisms of oxygen-sensing in human ductus arteriosus smooth muscle cells: A comprehensive transcriptome profile reveals a central role for mitochondria.
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Grant
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Impaired mitochondrial fusion in pulmonary arterial hypertension
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Grant
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O2 sensing in the human and rabbit ductus arteriosus.
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