 Chromogranins
"Chromogranins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of acidic proteins that are major components of SECRETORY GRANULES in the endocrine and neuroendocrine cells. They play important roles in the aggregation, packaging, sorting, and processing of secretory protein prior to secretion. They are cleaved to release biologically active peptides. There are various types of granins, usually classified by their sources.
| Descriptor ID |
D002864
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| MeSH Number(s) |
D12.776.641.199 D12.776.811.185
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Chromogranins".
Below are MeSH descriptors whose meaning is more specific than "Chromogranins".
This graph shows the total number of publications written about "Chromogranins" by people in this website by year, and whether "Chromogranins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1986 | 0 | 1 | 1 | | 1989 | 0 | 2 | 2 | | 1994 | 1 | 0 | 1 | | 1997 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2001 | 0 | 2 | 2 | | 2007 | 1 | 0 | 1 | | 2009 | 0 | 1 | 1 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Chromogranins" by people in Profiles.
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França MM, Levine RL, Pappa T, Ilaka-Chibuluzo S, Rothberger GD, Dumitrescu AM, Refetoff S. Nonautoimmune Hyperthyroidism Caused by a Somatic Mosaic GNAS Mutation Involving Part of the Thyroid Gland. Thyroid. 2020 04; 30(4):640-642.
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Ritterhouse LL, Vivero M, Mino-Kenudson M, Sholl LM, Iafrate AJ, Nardi V, Dong F. GNAS mutations in primary mucinous and non-mucinous lung adenocarcinomas. Mod Pathol. 2017 12; 30(12):1720-1727.
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Krishnan C, Twist CJ, Fu T, Arber DA. Detection of isolated tumor cells in neuroblastoma by immunohistochemical analysis in bone marrow biopsy specimens: improved detection with use of beta-catenin. Am J Clin Pathol. 2009 Jan; 131(1):49-57.
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Tanabe A, Yanagiya T, Iida A, Saito S, Sekine A, Takahashi A, Nakamura T, Tsunoda T, Kamohara S, Nakata Y, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Funahashi T, Miyazaki S, Tokunaga K, Hamaguchi K, Shimada T, Tanaka K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H, Sakata T, Matsuzawa Y, Kamatani N, Nakamura Y, Hotta K. Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity. J Clin Endocrinol Metab. 2007 Mar; 92(3):1145-54.
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Gerhard M, Neumayer N, Presecan-Siedel E, Zanner R, Lengyel E, Cramer T, Höcker M, Prinz C. Gastrin induces expression and promoter activity of the vesicular monoamine transporter subtype 2. Endocrinology. 2001 Aug; 142(8):3663-72.
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Abou-Saif A, Lei J, McDonald TJ, Chakrabarti S, Waxman IF, Shojamanesh H, Schrump DS, Kleiner DE, Gibril F, Jensen RT. A new cause of Zollinger-Ellison syndrome: non-small cell lung cancer. Gastroenterology. 2001 Apr; 120(5):1271-8.
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Kim SJ, Gonen D, Hanna GL, Leventhal BL, Cook EH. Deletion polymorphism in the coding region of the human NESP55 alternative transcript of GNAS1. Mol Cell Probes. 2000 Jun; 14(3):191-4.
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Speights VO, Cohen MK, Riggs MW, Coffield KS, Keegan G, Arber DA. Neuroendocrine stains and proliferative indices of prostatic adenocarcinomas in transurethral resection samples. Br J Urol. 1997 Aug; 80(2):281-6.
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Cohen MK, Arber DA, Coffield KS, Keegan GT, McClintock J, Speights VO. Neuroendocrine differentiation in prostatic adenocarcinoma and its relationship to tumor progression. Cancer. 1994 Oct 01; 74(7):1899-903.
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Guest PC, Rhodes CJ, Hutton JC. Regulation of the biosynthesis of insulin-secretory-granule proteins. Co-ordinate translational control is exerted on some, but not all, granule matrix constituents. Biochem J. 1989 Jan 15; 257(2):431-7.
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