"Fibrinogen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.
Descriptor ID |
D005340
|
MeSH Number(s) |
D12.776.124.050.250 D12.776.124.125.500 D12.776.811.300 D23.119.490
|
Concept/Terms |
Fibrinogen- Fibrinogen
- Blood Coagulation Factor I
- Coagulation Factor I
- Factor I, Coagulation
- Factor I
|
Below are MeSH descriptors whose meaning is more general than "Fibrinogen".
Below are MeSH descriptors whose meaning is more specific than "Fibrinogen".
This graph shows the total number of publications written about "Fibrinogen" by people in this website by year, and whether "Fibrinogen" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1998 | 0 | 1 | 1 |
1999 | 0 | 1 | 1 |
2000 | 1 | 2 | 3 |
2002 | 0 | 2 | 2 |
2005 | 0 | 1 | 1 |
2007 | 0 | 1 | 1 |
2008 | 0 | 1 | 1 |
2011 | 1 | 0 | 1 |
2012 | 0 | 1 | 1 |
2013 | 2 | 3 | 5 |
2014 | 1 | 1 | 2 |
2015 | 1 | 1 | 2 |
2016 | 0 | 1 | 1 |
2019 | 1 | 1 | 2 |
2020 | 0 | 1 | 1 |
2021 | 1 | 2 | 3 |
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Below are the most recent publications written about "Fibrinogen" by people in Profiles.
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Fibrinolytic Activation in Patients with Progressive Intracranial Hemorrhage after Traumatic Brain Injury. J Neurotrauma. 2021 04 15; 38(8):960-966.
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Estimated glucose disposal rate as a candidate biomarker for thrombotic biomarkers in T1D: a pooled analysis. J Endocrinol Invest. 2021 Nov; 44(11):2417-2426.
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Waning efficacy in a long-term AAV-mediated gene therapy study in the murine model of Krabbe disease. Mol Ther. 2021 05 05; 29(5):1883-1902.
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Basic principles of viscoelastic testing. Transfusion. 2020 10; 60 Suppl 6:S1-S9.
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?' fibrinogen levels are associated with blood clot strength in traumatic brain injury patients. Am J Surg. 2020 08; 220(2):459-463.
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Systemic Markers of Inflammation in Smokers With Symptoms Despite Preserved Spirometry in SPIROMICS. Chest. 2019 05; 155(5):908-917.
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The crystal structure of the ligand-binding region of serine-glutamate repeat containing protein A (SgrA) of Enterococcus faecium reveals a new protein fold: functional characterization and insights into its adhesion function. FEBS J. 2016 08; 283(16):3039-55.
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Elevated Levels of Serum Fibrin and Fibrinogen Degradation Products Are Independent Predictors of Larger Coronary Plaques and Greater Plaque Necrotic Core. Circ J. 2016; 80(4):931-7.
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The N-terminal domain of the thermo-regulated surface protein PrpA of Enterococcus faecium binds to fibrinogen, fibronectin and platelets. Sci Rep. 2015 Dec 17; 5:18255.
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Steroid therapy attenuates acute phase reactant response among children on ventricular assist device support. Ann Thorac Surg. 2015 Apr; 99(4):1392-8.