"Angiotensinogen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alpha-globulin of about 453 amino acids, depending on the species. It is produced by the liver and secreted into blood circulation. Angiotensinogen is the inactive precursor of natural angiotensins. Upon successive enzyme cleavages, angiotensinogen yields angiotensin I, II, and III with amino acids numbered at 10, 8, and 7, respectively.
| Descriptor ID |
D000808
|
| MeSH Number(s) |
D12.644.456.073.070 D12.644.861.020 D12.776.811.070 D12.776.872.020
|
| Concept/Terms |
Angiotensinogen- Angiotensinogen
- Serpin A8
- Renin-Substrate
- Renin Substrate
- Hypertensinogen
- Proangiotensin
|
Below are MeSH descriptors whose meaning is more general than "Angiotensinogen".
Below are MeSH descriptors whose meaning is more specific than "Angiotensinogen".
This graph shows the total number of publications written about "Angiotensinogen" by people in this website by year, and whether "Angiotensinogen" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2009 | 1 | 1 | 2 |
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Below are the most recent publications written about "Angiotensinogen" by people in Profiles.
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RNA Interference With Zilebesiran for Mild to Moderate Hypertension: The KARDIA-1 Randomized Clinical Trial. JAMA. 2024 03 05; 331(9):740-749.
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Zilebesiran, an RNA Interference Therapeutic Agent for Hypertension. N Engl J Med. 2023 Jul 20; 389(3):228-238.
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Angiotensinogen in Sex and Hypertension: New Insights From the Multi-Ethnic Study of Atherosclerosis (MESA). J Am Coll Cardiol. 2023 04 04; 81(13):1260-1262.
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Cardiovascular dysfunction in adult mice following postnatal intermittent hypoxia. Pediatr Res. 2015 Mar; 77(3):425-33.
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Long-term therapeutic effect of vitamin D analog doxercalciferol on diabetic nephropathy: strong synergism with AT1 receptor antagonist. Am J Physiol Renal Physiol. 2009 Sep; 297(3):F791-801.
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1,25-Dihydroxyvitamin D3 suppresses high glucose-induced angiotensinogen expression in kidney cells by blocking the NF-{kappa}B pathway. Am J Physiol Renal Physiol. 2009 May; 296(5):F1212-8.
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Combinational effect of genes for the renin-angiotensin system in conferring susceptibility to diabetic nephropathy. J Hum Genet. 2007; 52(2):143-151.
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Mechanical stretch/relaxation stimulates a cellular renin-angiotensin system in cultured rat mesangial cells. Exp Nephrol. 1998 Jan-Feb; 6(1):57-66.
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Adipogenesis in a murine bone marrow stromal cell line capable of supporting B lineage lymphocyte growth and proliferation: biochemical and molecular characterization. Eur J Immunol. 1990 Feb; 20(2):379-87.
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The renin-angiotensin system in mother and fetus at cesarean section: a preliminary communication. Perspect Nephrol Hypertens. 1976; 5:287-92.