Digoxin
"Digoxin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666)
Descriptor ID |
D004077
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MeSH Number(s) |
D04.808.155.160.349 D04.808.155.580.130.500.436 D09.408.180.261.436
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Concept/Terms |
Digacin- Digacin
- Lilly Brand of Digoxin
Digitek- Digitek
- Bertek Brand of Digoxin
- UDL Brand of Digoxin
Lanoxin- Lanoxin
- Glaxo Wellcome Brand of Digoxin
- GlaxoSmithKline Brand 1 of Digoxin
- Virco Brand of Digoxin
- Lanoxin-PG
- Lanoxin PG
- Lenoxin
Digoxine Nativelle- Digoxine Nativelle
- Nativelle, Digoxine
- Hemigoxine Nativelle
- Nativelle, Hemigoxine
- Proctor & Gamble Brand of Digoxin
Dilanacin- Dilanacin
- AWD.pharma Brand of Digoxin
Lanicor- Lanicor
- Teofarma Brand of Digoxin
Lanoxicaps- Lanoxicaps
- GlaxoSmithKline Brand 2 of Digoxin
Mapluxin- Mapluxin
- Novartis Brand of Digoxin
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Below are MeSH descriptors whose meaning is more general than "Digoxin".
Below are MeSH descriptors whose meaning is more specific than "Digoxin".
This graph shows the total number of publications written about "Digoxin" by people in this website by year, and whether "Digoxin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1985 | 1 | 1 | 2 | 1987 | 0 | 1 | 1 | 1988 | 1 | 0 | 1 | 1990 | 1 | 0 | 1 | 1991 | 1 | 0 | 1 | 1992 | 0 | 1 | 1 | 1997 | 0 | 1 | 1 | 2001 | 1 | 0 | 1 | 2002 | 0 | 1 | 1 | 2009 | 0 | 1 | 1 | 2011 | 0 | 1 | 1 | 2014 | 0 | 1 | 1 | 2016 | 1 | 0 | 1 | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Digoxin" by people in Profiles.
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Wang N, Shi XF, Khan SA, Wang B, Semenza GL, Prabhakar NR, Nanduri J. Hypoxia-inducible factor-1 mediates pancreatic ß-cell dysfunction by intermittent hypoxia. Am J Physiol Cell Physiol. 2020 11 01; 319(5):C922-C932.
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Shumaker AC, Bullard HM, Churpek J, Knoebel RW. Posaconazole-digoxin drug-drug interaction mediated by inhibition of P-glycoprotein. J Oncol Pharm Pract. 2019 Oct; 25(7):1758-1761.
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La J, Reed EB, Koltsova S, Akimova O, Hamanaka RB, Mutlu GM, Orlov SN, Dulin NO. Regulation of myofibroblast differentiation by cardiac glycosides. Am J Physiol Lung Cell Mol Physiol. 2016 05 01; 310(9):L815-23.
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Zhang DY, Anderson AS. The sympathetic nervous system and heart failure. Cardiol Clin. 2014 Feb; 32(1):33-45, vii.
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Yuan G, Khan SA, Luo W, Nanduri J, Semenza GL, Prabhakar NR. Hypoxia-inducible factor 1 mediates increased expression of NADPH oxidase-2 in response to intermittent hypoxia. J Cell Physiol. 2011 Nov; 226(11):2925-33.
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Cuneo BF, Lee M, Roberson D, Niksch A, Ovadia M, Parilla BV, Benson DW. A management strategy for fetal immune-mediated atrioventricular block. J Matern Fetal Neonatal Med. 2010 Dec; 23(12):1400-5.
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Donlan SM, Quattromani E, Pang PS, Gheorghiade M. Therapy for acute heart failure syndromes. Curr Cardiol Rep. 2009 May; 11(3):192-201.
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Holaska JM, Black BE, Rastinejad F, Paschal BM. Ca2+-dependent nuclear export mediated by calreticulin. Mol Cell Biol. 2002 Sep; 22(17):6286-97.
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Xie JT, Dey L, Yuan CS. Biphasic effect of cardiac glycosides on action potential duration in isolated Purkinje fibers. Pharmacol Toxicol. 2001 Sep; 89(3):145-8.
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Guerriero SE, Ehrenpreis E, Gallagher KL. Two cases of clarithromycin-induced digoxin toxicity. Pharmacotherapy. 1997 Sep-Oct; 17(5):1035-7.
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