 Astrocytes
"Astrocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from "star" cells) are irregularly shaped with many long processes, including those with "end feet" which form the glial (limiting) membrane and directly and indirectly contribute to the BLOOD-BRAIN BARRIER. They regulate the extracellular ionic and chemical environment, and "reactive astrocytes" (along with MICROGLIA) respond to injury.
| Descriptor ID |
D001253
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| MeSH Number(s) |
A08.637.200 A11.650.200
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Astrocytes".
Below are MeSH descriptors whose meaning is more specific than "Astrocytes".
This graph shows the total number of publications written about "Astrocytes" by people in this website by year, and whether "Astrocytes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 1 | 1 | | 1984 | 0 | 1 | 1 | | 1985 | 1 | 1 | 2 | | 1986 | 1 | 0 | 1 | | 1987 | 2 | 0 | 2 | | 1989 | 2 | 0 | 2 | | 1990 | 2 | 0 | 2 | | 1991 | 2 | 1 | 3 | | 1992 | 0 | 2 | 2 | | 1993 | 1 | 1 | 2 | | 1994 | 1 | 1 | 2 | | 1995 | 3 | 1 | 4 | | 1996 | 2 | 3 | 5 | | 1997 | 4 | 1 | 5 | | 1998 | 5 | 1 | 6 | | 1999 | 1 | 1 | 2 | | 2000 | 1 | 5 | 6 | | 2001 | 3 | 0 | 3 | | 2002 | 1 | 0 | 1 | | 2003 | 1 | 1 | 2 | | 2004 | 1 | 4 | 5 | | 2006 | 3 | 2 | 5 | | 2007 | 1 | 2 | 3 | | 2008 | 4 | 0 | 4 | | 2009 | 0 | 3 | 3 | | 2010 | 2 | 3 | 5 | | 2011 | 5 | 3 | 8 | | 2012 | 3 | 0 | 3 | | 2013 | 1 | 2 | 3 | | 2014 | 3 | 1 | 4 | | 2015 | 1 | 5 | 6 | | 2016 | 4 | 2 | 6 | | 2017 | 3 | 2 | 5 | | 2018 | 1 | 1 | 2 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Astrocytes" by people in Profiles.
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Borenstein R, Hanson BA, Markosyan RM, Gallo ES, Narasipura SD, Bhutta M, Shechter O, Lurain NS, Cohen FS, Al-Harthi L, Nicholson DA. Ginkgolic acid inhibits fusion of enveloped viruses. Sci Rep. 2020 03 16; 10(1):4746.
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Nascimento BPP, Bocco BMLC, Fernandes GW, Fonseca TL, McAninch EA, Cardoso CV, Bondan EF, Nassif RJ, Cysneiros RM, Bianco AC, Ribeiro MO. Induction of Type 2 Iodothyronine Deiodinase After Status Epilepticus Modifies Hippocampal Gene Expression in Male Mice. Endocrinology. 2018 08 01; 159(8):3090-3104.
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Chen J, Van Gulden S, McGuire TL, Fleming AC, Oka C, Kessler JA, Peng CY. BMP-Responsive Protease HtrA1 Is Differentially Expressed in Astrocytes and Regulates Astrocytic Development and Injury Response. J Neurosci. 2018 04 11; 38(15):3840-3857.
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Yin B, Barrionuevo G, Weber SG. Mitochondrial GSH Systems in CA1 Pyramidal Cells and Astrocytes React Differently during Oxygen-Glucose Deprivation and Reperfusion. ACS Chem Neurosci. 2018 04 18; 9(4):738-748.
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Kaverina N, Borovjagin AV, Kadagidze Z, Baryshnikov A, Baryshnikova M, Malin D, Ghosh D, Shah N, Welch DR, Gabikian P, Karseladze A, Cobbs C, Ulasov IV. Astrocytes promote progression of breast cancer metastases to the brain via a KISS1-mediated autophagy. Autophagy. 2017; 13(11):1905-1923.
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Ihse E, Yamakado H, van Wijk XM, Lawrence R, Esko JD, Masliah E. Cellular internalization of alpha-synuclein aggregates by cell surface heparan sulfate depends on aggregate conformation and cell type. Sci Rep. 2017 08 21; 7(1):9008.
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Fang H, Song P, Shen Y, Shen C, Liu X. Bone mesenchymal stem cell-conditioned medium decreases the generation of astrocytes during the process of neural stem cells differentiation. J Spinal Cord Med. 2018 01; 41(1):10-16.
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Singh DK, Kollipara RK, Vemireddy V, Yang XL, Sun Y, Regmi N, Klingler S, Hatanpaa KJ, Raisanen J, Cho SK, Sirasanagandla S, Nannepaga S, Piccirillo S, Mashimo T, Wang S, Humphries CG, Mickey B, Maher EA, Zheng H, Kim RS, Kittler R, Bachoo RM. Oncogenes Activate an Autonomous Transcriptional Regulatory Circuit That Drives Glioblastoma. Cell Rep. 2017 01 24; 18(4):961-976.
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Cortes M, Cao M, Liu HL, Burns P, Moore C, Fecteau G, Desrochers A, Barreiro LB, Antel JP, Frasch MG. RNAseq profiling of primary microglia and astrocyte cultures in near-term ovine fetus: A glial in vivo-in vitro multi-hit paradigm in large mammalian brain. J Neurosci Methods. 2017 01 30; 276:23-32.
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Rivas JR, Ireland SJ, Chkheidze R, Rounds WH, Lim J, Johnson J, Ramirez DM, Ligocki AJ, Chen D, Guzman AA, Woodhall M, Wilson PC, Meffre E, White C, Greenberg BM, Waters P, Cowell LG, Stowe AM, Monson NL. Peripheral VH4+ plasmablasts demonstrate autoreactive B cell expansion toward brain antigens in early multiple sclerosis patients. Acta Neuropathol. 2017 01; 133(1):43-60.
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