 Cholesterol 7-alpha-Hydroxylase
"Cholesterol 7-alpha-Hydroxylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A membrane-bound cytochrome P450 enzyme that catalyzes the 7-alpha-hydroxylation of CHOLESTEROL in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP7, converts cholesterol to 7-alpha-hydroxycholesterol which is the first and rate-limiting step in the synthesis of BILE ACIDS.
| Descriptor ID |
D002790
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| MeSH Number(s) |
D08.244.453.915.200 D08.811.682.690.708.170.915.200 D08.811.682.690.708.783.200 D12.776.422.220.453.915.200
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| Concept/Terms |
Cholesterol 7-alpha-Hydroxylase- Cholesterol 7-alpha-Hydroxylase
- Cholesterol 7 alpha Hydroxylase
- Cholesterol 7alpha-Hydroxylase
- Cholesterol 7alpha Hydroxylase
- Cholesterol-7-Hydroxylase
- Cholesterol 7 Hydroxylase
- Cytochrome P450 7
- CYP 7A
- CYP7
- CYP7A
- Cytochrome P-450 CYP7
- Cytochrome P 450 CYP7
- Cholesterol 7-alpha-Monooxygenase
- Cholesterol 7 alpha Monooxygenase
- CYP 7
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Below are MeSH descriptors whose meaning is more general than "Cholesterol 7-alpha-Hydroxylase".
Below are MeSH descriptors whose meaning is more specific than "Cholesterol 7-alpha-Hydroxylase".
This graph shows the total number of publications written about "Cholesterol 7-alpha-Hydroxylase" by people in this website by year, and whether "Cholesterol 7-alpha-Hydroxylase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cholesterol 7-alpha-Hydroxylase" by people in Profiles.
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Wang J, Ji J, Song Z, Zhang W, He X, Li F, Zhang C, Guo C, Wang C, Yuan C. Hypocholesterolemic effect of emodin by simultaneous determination of in vitro and in vivo bile salts binding. Fitoterapia. 2016 Apr; 110:116-22.
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Li W, Wang D, Qin J, Liu C, Zhang Q, Zhang X, Yu X, Lahn BT, Mao FF, Xiang AP. Generation of functional hepatocytes from mouse induced pluripotent stem cells. J Cell Physiol. 2010 Mar; 222(3):492-501.
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Hashimoto K, Cohen RN, Yamada M, Markan KR, Monden T, Satoh T, Mori M, Wondisford FE. Cross-talk between thyroid hormone receptor and liver X receptor regulatory pathways is revealed in a thyroid hormone resistance mouse model. J Biol Chem. 2006 Jan 06; 281(1):295-302.
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