 Kinins
"Kinins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A generic term used to describe a group of polypeptides with related chemical structures and pharmacological properties that are widely distributed in nature. These peptides are AUTACOIDS that act locally to produce pain, vasodilatation, increased vascular permeability, and the synthesis of prostaglandins. Thus, they comprise a subset of the large number of mediators that contribute to the inflammatory response. (From Goodman and Gilman's The Pharmacologic Basis of Therapeutics, 8th ed, p588)
| Descriptor ID |
D007705
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| MeSH Number(s) |
D12.644.276.812 D12.776.467.812 D23.469.050.375 D23.529.812
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Kinins".
Below are MeSH descriptors whose meaning is more specific than "Kinins".
This graph shows the total number of publications written about "Kinins" by people in this website by year, and whether "Kinins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1983 | 1 | 0 | 1 | | 1985 | 1 | 4 | 5 | | 1986 | 5 | 4 | 9 | | 1987 | 1 | 3 | 4 | | 1988 | 2 | 1 | 3 | | 1989 | 1 | 0 | 1 | | 1990 | 3 | 1 | 4 | | 1992 | 0 | 2 | 2 | | 1997 | 0 | 1 | 1 |
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Below are the most recent publications written about "Kinins" by people in Profiles.
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Naclerio RM, Proud D, Moylan B, Balcer S, Freidhoff L, Kagey-Sobotka A, Lichtenstein LM, Creticos PS, Hamilton RG, Norman PS. A double-blind study of the discontinuation of ragweed immunotherapy. J Allergy Clin Immunol. 1997 Sep; 100(3):293-300.
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Naclerio RM. Inhibition of mediator release during the early reaction to antigen. J Allergy Clin Immunol. 1992 Oct; 90(4 Pt 2):715-9.
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Shin MH, Baroody F, Proud D, Kagey-Sobotka A, Lichtenstein LM, Naclerio RM. The effect of azelastine on the early allergic response. Clin Exp Allergy. 1992 Feb; 22(2):289-95.
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Iliopoulos O, Proud D, Adkinson NF, Norman PS, Kagey-Sobotka A, Lichtenstein LM, Naclerio RM. Relationship between the early, late, and rechallenge reaction to nasal challenge with antigen: observations on the role of inflammatory mediators and cells. J Allergy Clin Immunol. 1990 Dec; 86(6 Pt 1):851-61.
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Farr BM, Gwaltney JM, Hendley JO, Hayden FG, Naclerio RM, McBride T, Doyle WJ, Sorrentino JV, Riker DK, Proud D. A randomized controlled trial of glucocorticoid prophylaxis against experimental rhinovirus infection. J Infect Dis. 1990 Nov; 162(5):1173-7.
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Proud D, Naclerio RM, Gwaltney JM, Hendley JO. Kinins are generated in nasal secretions during natural rhinovirus colds. J Infect Dis. 1990 Jan; 161(1):120-3.
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Proud D, Naclerio RM, Meyers DA, Kagey-Sobotka A, Lichtenstein LM, Valentine MD. Effects of a single-dose pretreatment with captopril on the immediate response to nasal challenge with allergen. Int Arch Allergy Appl Immunol. 1990; 93(2-3):165-70.
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Proud D, Hendley JO, Gwaltney JM, Naclerio RM. Recent studies on the rule of kinins in inflammatory diseases of human airways. Adv Exp Med Biol. 1989; 247A:117-23.
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Silber G, Proud D, Warner J, Naclerio R, Kagey-Sobotka A, Lichtenstein L, Eggleston P. In vivo release of inflammatory mediators by hyperosmolar solutions. Am Rev Respir Dis. 1988 Mar; 137(3):606-12.
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Naclerio RM, Proud D, Kagey-Sobotka A, Lichtenstein LM, Hendley JO, Gwaltney JM. Is histamine responsible for the symptoms of rhinovirus colds? A look at the inflammatory mediators following infection. Pediatr Infect Dis J. 1988 Mar; 7(3):218-22.
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