"Protein Conformation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).
| Descriptor ID |
D011487
|
| MeSH Number(s) |
G02.111.570.820.709
|
| Concept/Terms |
Protein Conformation- Protein Conformation
- Conformation, Protein
- Conformations, Protein
- Protein Conformations
|
Below are MeSH descriptors whose meaning is more general than "Protein Conformation".
Below are MeSH descriptors whose meaning is more specific than "Protein Conformation".
This graph shows the total number of publications written about "Protein Conformation" by people in this website by year, and whether "Protein Conformation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 10 | 11 |
| 1996 | 5 | 13 | 18 |
| 1997 | 5 | 8 | 13 |
| 1998 | 4 | 16 | 20 |
| 1999 | 1 | 18 | 19 |
| 2000 | 0 | 16 | 16 |
| 2001 | 0 | 15 | 15 |
| 2002 | 3 | 22 | 25 |
| 2003 | 1 | 27 | 28 |
| 2004 | 3 | 30 | 33 |
| 2005 | 2 | 29 | 31 |
| 2006 | 0 | 31 | 31 |
| 2007 | 5 | 24 | 29 |
| 2008 | 2 | 24 | 26 |
| 2009 | 3 | 26 | 29 |
| 2010 | 4 | 22 | 26 |
| 2011 | 3 | 18 | 21 |
| 2012 | 2 | 24 | 26 |
| 2013 | 5 | 14 | 19 |
| 2014 | 4 | 17 | 21 |
| 2015 | 2 | 22 | 24 |
| 2016 | 1 | 31 | 32 |
| 2017 | 1 | 15 | 16 |
| 2018 | 3 | 30 | 33 |
| 2019 | 4 | 14 | 18 |
| 2020 | 0 | 14 | 14 |
| 2021 | 2 | 17 | 19 |
| 2022 | 1 | 5 | 6 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 9 | 9 |
| 2025 | 0 | 3 | 3 |
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Below are the most recent publications written about "Protein Conformation" by people in Profiles.
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Energy landscape of a Kv channel revealed by temperature steps while perturbing its electromechanical coupling. Nat Commun. 2025 Apr 09; 16(1):3379.
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Structural studies of the IFN?4 receptor complex using cryoEM enabled by protein engineering. Nat Commun. 2025 Jan 18; 16(1):818.
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Direct visualization of electric-field-stimulated ion conduction in a potassium channel. Cell. 2025 Jan 09; 188(1):77-88.e15.
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Mechanisms underlying modulation of human GlyRa3 by Zn2+ and pH. Sci Adv. 2024 12 20; 10(51):eadr5920.
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Collapse and Protein Folding: Should We Be Surprised That Biothermodynamics Works So Well? Annu Rev Biophys. 2025 May; 54(1):17-34.
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Conformational coupling between extracellular and transmembrane domains modulates holo-adhesion GPCR function. Nat Commun. 2024 12 04; 15(1):10545.
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Isoleucine gate blocks K+ conduction in C-type inactivation. Elife. 2024 Nov 12; 13.
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Unraveling the Membrane Topology of TMEM151A: A Step Towards Understanding its Cellular Role. J Mol Biol. 2024 Dec 01; 436(23):168834.
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A Method for Treating Significant Conformational Changes in Alchemical Free Energy Simulations of Protein-Ligand Binding. J Chem Theory Comput. 2024 Oct 08; 20(19):8609-8623.
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Serial X-ray liquidography: multi-dimensional assay framework for exploring biomolecular structural dynamics with microgram quantities. Nat Commun. 2024 Jul 26; 15(1):6287.