"Protein Conformation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).
| Descriptor ID |
D011487
|
| MeSH Number(s) |
G02.111.570.820.709
|
| Concept/Terms |
Protein Conformation- Protein Conformation
- Conformation, Protein
- Conformations, Protein
- Protein Conformations
|
Below are MeSH descriptors whose meaning is more general than "Protein Conformation".
Below are MeSH descriptors whose meaning is more specific than "Protein Conformation".
This graph shows the total number of publications written about "Protein Conformation" by people in this website by year, and whether "Protein Conformation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 5 | 12 | 17 |
| 1997 | 5 | 9 | 14 |
| 1998 | 4 | 16 | 20 |
| 1999 | 1 | 18 | 19 |
| 2000 | 0 | 15 | 15 |
| 2001 | 0 | 15 | 15 |
| 2002 | 2 | 22 | 24 |
| 2003 | 1 | 27 | 28 |
| 2004 | 3 | 31 | 34 |
| 2005 | 2 | 30 | 32 |
| 2006 | 0 | 32 | 32 |
| 2007 | 5 | 24 | 29 |
| 2008 | 2 | 23 | 25 |
| 2009 | 3 | 26 | 29 |
| 2010 | 4 | 20 | 24 |
| 2011 | 3 | 17 | 20 |
| 2012 | 2 | 24 | 26 |
| 2013 | 5 | 14 | 19 |
| 2014 | 5 | 17 | 22 |
| 2015 | 2 | 23 | 25 |
| 2016 | 1 | 33 | 34 |
| 2017 | 1 | 17 | 18 |
| 2018 | 4 | 29 | 33 |
| 2019 | 4 | 15 | 19 |
| 2020 | 1 | 18 | 19 |
| 2021 | 2 | 22 | 24 |
| 2022 | 1 | 6 | 7 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 10 | 10 |
| 2025 | 0 | 10 | 10 |
| 2026 | 0 | 4 | 4 |
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Below are the most recent publications written about "Protein Conformation" by people in Profiles.
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Characterization and modulation of human insulin degrading enzyme conformational dynamics to control enzyme activity. Elife. 2026 Jun 08; 14.
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Human GlyRa2 pore dynamics in gating and inhibition. Structure. 2026 May 07; 34(5):798-813.e7.
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Protein Structure Determination by Racemic and Quasi-Racemic X-Ray Crystallography. Chembiochem. 2026 Feb 25; 27(4):e202500950.
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Conformational ensembles of the magnesium channel CorA reveal structural basis for channel gating. Proc Natl Acad Sci U S A. 2026 Feb 24; 123(8):e2512532123.
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Force field sensitivity of ion occupancy in potassium channels. Biophys J. 2026 Aug 18; 125(16):4131-4146.
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Closed state structure of the pore revealed by uncoupled Shaker K+ channel. Nat Commun. 2025 Nov 19; 16(1):10180.
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Cryo-EM structure of phospholipase Ce defines N-terminal domains and their roles in activity. Commun Biol. 2025 Oct 06; 8(1):1429.
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Protein Kinase A Phosphorylates a Conformationally High-energy State of Raf Kinase Inhibitory Protein. J Mol Biol. 2025 Dec 01; 437(23):169466.
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Dimerization and dynamics of human angiotensin-I converting enzyme revealed by cryo-EM and MD simulations. Elife. 2025 Sep 24; 14.
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Conformational dynamics and multimodal interaction of Paxillin with the focal adhesion targeting domain. Sci Adv. 2025 Jun 20; 11(25):eadt9936.