 Gramicidin
"Gramicidin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of peptide antibiotics from BACILLUS brevis. Gramicidin C or S is a cyclic, ten-amino acid polypeptide and gramicidins A, B, D are linear. Gramicidin is one of the two principal components of TYROTHRICIN which is used topically for gram-positive organisms. It is toxic to blood, liver, kidneys, meninges, and the olfactory apparatus.
| Descriptor ID |
D006096
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| MeSH Number(s) |
D04.345.566.850.300 D12.644.641.850.300 D12.644.905.300 D12.776.543.695.221
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Gramicidin".
Below are MeSH descriptors whose meaning is more specific than "Gramicidin".
This graph shows the total number of publications written about "Gramicidin" by people in this website by year, and whether "Gramicidin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1988 | 1 | 0 | 1 | | 1990 | 1 | 0 | 1 | | 1991 | 1 | 0 | 1 | | 1992 | 1 | 0 | 1 | | 1994 | 3 | 0 | 3 | | 1995 | 1 | 0 | 1 | | 1996 | 3 | 0 | 3 | | 1997 | 2 | 0 | 2 | | 1999 | 1 | 2 | 3 | | 2000 | 2 | 1 | 3 | | 2001 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2004 | 1 | 0 | 1 | | 2006 | 1 | 1 | 2 | | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Gramicidin" by people in Profiles.
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Roux B. Calculating the Effect of Membrane Thickness on the Lifetime of the Gramicidin A Channel: A Landmark. Biophys J. 2019 11 19; 117(10):1779-1780.
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Allen TW, Andersen OS, Roux B. Molecular dynamics - potential of mean force calculations as a tool for understanding ion permeation and selectivity in narrow channels. Biophys Chem. 2006 Dec 01; 124(3):251-67.
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Allen TW, Andersen OS, Roux B. Ion permeation through a narrow channel: using gramicidin to ascertain all-atom molecular dynamics potential of mean force methodology and biomolecular force fields. Biophys J. 2006 May 15; 90(10):3447-68.
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Allen TW, Andersen OS, Roux B. On the importance of atomic fluctuations, protein flexibility, and solvent in ion permeation. J Gen Physiol. 2004 Dec; 124(6):679-90.
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Allen TW, Andersen OS, Roux B. Structure of gramicidin a in a lipid bilayer environment determined using molecular dynamics simulations and solid-state NMR data. J Am Chem Soc. 2003 Aug 13; 125(32):9868-77.
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Schumaker MF, Pomès R, Roux B. Framework model for single proton conduction through gramicidin. Biophys J. 2001 Jan; 80(1):12-30.
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Schumaker MF, Pomès R, Roux B. A combined molecular dynamics and diffusion model of single proton conduction through gramicidin. Biophys J. 2000 Dec; 79(6):2840-57.
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Lagüe P, Zuckermann MJ, Roux B. Lipid-mediated interactions between intrinsic membrane proteins: a theoretical study based on integral equations. Biophys J. 2000 Dec; 79(6):2867-79.
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Sung KW, Kirby M, McDonald MP, Lovinger DM, Delpire E. Abnormal GABAA receptor-mediated currents in dorsal root ganglion neurons isolated from Na-K-2Cl cotransporter null mice. J Neurosci. 2000 Oct 15; 20(20):7531-8.
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Roux B. Proton wires are different. Biophys J. 1999 Nov; 77(5):2331-2.
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