"src-Family Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A PROTEIN-TYROSINE KINASE family that was originally identified by homology to the Rous sarcoma virus ONCOGENE PROTEIN PP60(V-SRC). They interact with a variety of cell-surface receptors and participate in intracellular signal transduction pathways. Oncogenic forms of src-family kinases can occur through altered regulation or expression of the endogenous protein and by virally encoded src (v-src) genes.
| Descriptor ID |
D019061
|
| MeSH Number(s) |
D08.811.913.696.620.682.725.800
|
| Concept/Terms |
src-Family Kinases- src-Family Kinases
- src Family Kinases
- src-Family Tyrosine Kinases
- Tyrosine Kinases, src-Family
- src Family Tyrosine Kinases
- src Tyrosine Kinases
- Kinases, src Tyrosine
- Tyrosine Kinases, src
- Protein-Tyrosine Kinases, src
- Kinases, src Protein-Tyrosine
- src Protein-Tyrosine Kinases
- src Kinases
- Kinases, src
|
Below are MeSH descriptors whose meaning is more general than "src-Family Kinases".
Below are MeSH descriptors whose meaning is more specific than "src-Family Kinases".
This graph shows the total number of publications written about "src-Family Kinases" by people in this website by year, and whether "src-Family Kinases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 0 | 2 |
| 1995 | 1 | 1 | 2 |
| 1996 | 2 | 0 | 2 |
| 1997 | 1 | 2 | 3 |
| 1998 | 2 | 1 | 3 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 2 | 3 |
| 2001 | 0 | 1 | 1 |
| 2002 | 2 | 3 | 5 |
| 2003 | 2 | 2 | 4 |
| 2004 | 1 | 3 | 4 |
| 2005 | 0 | 2 | 2 |
| 2006 | 2 | 1 | 3 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 2 | 3 |
| 2010 | 0 | 7 | 7 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 1 | 2 |
| 2014 | 2 | 1 | 3 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 2 | 3 |
| 2017 | 0 | 2 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "src-Family Kinases" by people in Profiles.
-
Angiotensin II-Induced Long Non-Coding RNA Alivec Regulates Chondrogenesis in Vascular Smooth Muscle Cells. Cells. 2021 10 09; 10(10).
-
Attenuation of SRC Kinase Activity Augments PARP Inhibitor-mediated Synthetic Lethality in BRCA2-altered Prostate Tumors. Clin Cancer Res. 2021 03 15; 27(6):1792-1806.
-
Inhibition of porcine epidemic diarrhea virus (PEDV) replication by A77 1726 through targeting JAK and Src tyrosine kinases. Virology. 2020 12; 551:75-83.
-
?-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A. Mol Cell. 2019 12 19; 76(6):857-871.e9.
-
Tyrosine Kinase Activation and Conformational Flexibility: Lessons from Src-Family Tyrosine Kinases. Acc Chem Res. 2017 05 16; 50(5):1193-1201.
-
Selective Targeting of SH2 Domain-Phosphotyrosine Interactions of Src Family Tyrosine Kinases with Monobodies. J Mol Biol. 2017 05 05; 429(9):1364-1380.
-
CD8+ T cells stimulate Na-Cl co-transporter NCC in distal convoluted tubules leading to salt-sensitive hypertension. Nat Commun. 2017 01 09; 8:14037.
-
RETRACTED: The receptor tyrosine kinase AXL mediates nuclear translocation of the epidermal growth factor receptor. Sci Signal. 2017 01 03; 10(460).
-
The Activation of c-Src Tyrosine Kinase: Conformational Transition Pathway and Free Energy Landscape. J Phys Chem B. 2017 04 20; 121(15):3352-3363.
-
Transition path theory analysis of c-Src kinase activation. Proc Natl Acad Sci U S A. 2016 08 16; 113(33):9193-8.