"Cadherins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Calcium-dependent cell adhesion proteins. They are important in the formation of ADHERENS JUNCTIONS between cells. Cadherins are classified by their distinct immunological and tissue specificities, either by letters (E- for epithelial, N- for neural, and P- for placental cadherins) or by numbers (cadherin-12 or N-cadherin 2 for brain-cadherin). Cadherins promote cell adhesion via a homophilic mechanism as in the construction of tissues and of the whole animal body.
| Descriptor ID |
D015820
|
| MeSH Number(s) |
D12.776.395.550.200.200 D12.776.543.550.200.200 D23.050.301.350.200
|
| Concept/Terms |
P-Cadherins- P-Cadherins
- P Cadherins
- P-Cadherin
- P Cadherin
- Placental Cadherins
- Cadherins, Placental
- Cadherin-3
- Cadherin 3
E-Cadherins- E-Cadherins
- E Cadherins
- Uvomorulin
- Epithelial-Cadherins
- Epithelial Cadherins
- Cadherin-1
- Cadherin 1
- E-Cadherin
- E Cadherin
N-Cadherins- N-Cadherins
- N Cadherins
- N-Cadherin
- N Cadherin
- Neural Cadherins
- Cadherins, Neural
- Cadherin-2
- Cadherin 2
|
Below are MeSH descriptors whose meaning is more general than "Cadherins".
Below are MeSH descriptors whose meaning is more specific than "Cadherins".
This graph shows the total number of publications written about "Cadherins" by people in this website by year, and whether "Cadherins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1995 | 2 | 0 | 2 |
| 1997 | 1 | 0 | 1 |
| 1998 | 2 | 1 | 3 |
| 1999 | 1 | 1 | 2 |
| 2000 | 2 | 1 | 3 |
| 2001 | 2 | 1 | 3 |
| 2002 | 3 | 1 | 4 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 1 | 2 |
| 2005 | 1 | 1 | 2 |
| 2006 | 1 | 2 | 3 |
| 2007 | 3 | 0 | 3 |
| 2008 | 4 | 2 | 6 |
| 2009 | 4 | 4 | 8 |
| 2010 | 3 | 4 | 7 |
| 2011 | 1 | 4 | 5 |
| 2012 | 4 | 1 | 5 |
| 2013 | 2 | 0 | 2 |
| 2014 | 2 | 4 | 6 |
| 2015 | 1 | 6 | 7 |
| 2016 | 4 | 6 | 10 |
| 2017 | 5 | 1 | 6 |
| 2018 | 0 | 4 | 4 |
| 2019 | 1 | 3 | 4 |
| 2020 | 1 | 2 | 3 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 5 | 5 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cadherins" by people in Profiles.
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Fat2 polarizes Lar and Sema5c to coordinate the motility of collectively migrating epithelial cells. J Cell Sci. 2024 03 01; 137(5).
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Epidermal stratification requires retromer-mediated desmoglein-1 recycling. Dev Cell. 2022 12 19; 57(24):2683-2698.e8.
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Fat2 polarizes the WAVE complex in trans to align cell protrusions for collective migration. Elife. 2022 09 26; 11.
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Colorectal Neoplasia in CDH1 Pathogenic Variant Carriers: A Multicenter Analysis. Am J Gastroenterol. 2022 11 01; 117(11):1877-1879.
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Force-dependent intercellular adhesion strengthening underlies asymmetric adherens junction contraction. Curr Biol. 2022 05 09; 32(9):1986-2000.e5.
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Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB. J Allergy Clin Immunol. 2022 09; 150(3):622-630.
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Insights image for "Circulating extracellular vesicles from patients with acute chest syndrome disrupt adherens junctions between endothelial cells". Pediatr Res. 2021 03; 89(4):1036.
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Selection of Oncogenic Mutant Clones in Normal Human Skin Varies with Body Site. Cancer Discov. 2021 02; 11(2):340-361.
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Circulating extracellular vesicles from patients with acute chest syndrome disrupt adherens junctions between endothelial cells. Pediatr Res. 2021 03; 89(4):776-784.
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Phospholipase D2 restores endothelial barrier function by promoting PTPN14-mediated VE-cadherin dephosphorylation. J Biol Chem. 2020 05 29; 295(22):7669-7685.