Tosylphenylalanyl Chloromethyl Ketone
"Tosylphenylalanyl Chloromethyl Ketone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An inhibitor of Serine Endopeptidases. Acts as alkylating agent and is known to interfere with the translation process.
| Descriptor ID |
D014108
|
| MeSH Number(s) |
D02.455.426.559.389.832.710 D02.886.590.887.660 D12.125.065.930
|
| Concept/Terms |
Tosylphenylalanyl Chloromethyl Ketone- Tosylphenylalanyl Chloromethyl Ketone
- Chloromethyl Ketone, Tosylphenylalanyl
- Ketone, Tosylphenylalanyl Chloromethyl
- Tosylphenylalanyl Chloromethane
- Chloromethane, Tosylphenylalanyl
- TPCK
- Chlorophenyltosylamidobutanone
|
Below are MeSH descriptors whose meaning is more general than "Tosylphenylalanyl Chloromethyl Ketone".
Below are MeSH descriptors whose meaning is more specific than "Tosylphenylalanyl Chloromethyl Ketone".
This graph shows the total number of publications written about "Tosylphenylalanyl Chloromethyl Ketone" by people in this website by year, and whether "Tosylphenylalanyl Chloromethyl Ketone" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tosylphenylalanyl Chloromethyl Ketone" by people in Profiles.
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Caspase-3 triggers a TPCK-sensitive protease pathway leading to degradation of the BH3-only protein puma. Apoptosis. 2010 Dec; 15(12):1529-39.
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Proteolytic cleavage of VP1-2 is required for release of herpes simplex virus 1 DNA into the nucleus. J Virol. 2008 Apr; 82(7):3311-9.