"Virus Latency" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The ability of a pathogenic virus to lie dormant within a cell (latent infection). In eukaryotes, subsequent activation and viral replication is thought to be caused by extracellular stimulation of cellular transcription factors. Latency in bacteriophage is maintained by the expression of virally encoded repressors.
| Descriptor ID |
D017735
|
| MeSH Number(s) |
G06.920.900
|
| Concept/Terms |
Virus Latency- Virus Latency
- Latencies, Virus
- Latency, Virus
- Virus Latencies
- Viral Latency
- Latencies, Viral
- Latency, Viral
- Viral Latencies
|
Below are MeSH descriptors whose meaning is more general than "Virus Latency".
Below are MeSH descriptors whose meaning is more specific than "Virus Latency".
This graph shows the total number of publications written about "Virus Latency" by people in this website by year, and whether "Virus Latency" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 1 | 2 |
| 1998 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 2 | 0 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 2 | 1 | 3 |
| 2013 | 2 | 1 | 3 |
| 2014 | 2 | 0 | 2 |
| 2015 | 2 | 0 | 2 |
| 2018 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 2 | 2 |
| 2023 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Virus Latency" by people in Profiles.
-
Decitabine disrupts EBV genomic epiallele DNA methylation patterns around CTCF binding sites to increase chromatin accessibility and lytic transcription in gastric cancer. mBio. 2023 Oct 31; 14(5):e0039623.
-
The nuclear lamina binds the EBV genome during latency and regulates viral gene expression. PLoS Pathog. 2022 04; 18(4):e1010400.
-
The three-dimensional structure of Epstein-Barr virus genome varies by latency type and is regulated by PARP1 enzymatic activity. Nat Commun. 2022 01 17; 13(1):187.
-
Stress-Induced Epstein-Barr Virus Reactivation. Biomolecules. 2021 09 18; 11(9).
-
Nonsense-mediated decay controls the reactivation of the oncogenic herpesviruses EBV and KSHV. PLoS Biol. 2021 02; 19(2):e3001097.
-
PARP1 Stabilizes CTCF Binding and Chromatin Structure To Maintain Epstein-Barr Virus Latency Type. J Virol. 2018 09 15; 92(18).
-
Role of activating transcription factor 3 in the synthesis of latency-associated transcript and maintenance of herpes simplex virus 1 in latent state in ganglia. Proc Natl Acad Sci U S A. 2015 Sep 29; 112(39):E5420-6.
-
The 3 facets of regulation of herpes simplex virus gene expression: A critical inquiry. Virology. 2015 May; 479-480:562-7.
-
Patterns of accumulation of miRNAs encoded by herpes simplex virus during productive infection, latency, and on reactivation. Proc Natl Acad Sci U S A. 2015 Jan 06; 112(1):E49-55.
-
Broadly neutralizing antibodies and viral inducers decrease rebound from HIV-1 latent reservoirs in humanized mice. Cell. 2014 Aug 28; 158(5):989-999.