 Herpesvirus 1, Human
"Herpesvirus 1, Human" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The type species of SIMPLEXVIRUS causing most forms of non-genital herpes simplex in humans. Primary infection occurs mainly in infants and young children and then the virus becomes latent in the dorsal root ganglion. It then is periodically reactivated throughout life causing mostly benign conditions.
| Descriptor ID |
D018259
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| MeSH Number(s) |
B04.280.382.100.750.390 B04.909.204.382.100.750.390
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| Concept/Terms |
Herpesvirus 1, Human- Herpesvirus 1, Human
- Herpes Simplex Virus 1
- Human herpesvirus 1
- HHV-1
- HSV-1
- Herpes Simplex Virus Type 1
- Herpesvirus 1 (alpha), Human
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Below are MeSH descriptors whose meaning is more general than "Herpesvirus 1, Human".
Below are MeSH descriptors whose meaning is more specific than "Herpesvirus 1, Human".
This graph shows the total number of publications written about "Herpesvirus 1, Human" by people in this website by year, and whether "Herpesvirus 1, Human" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 3 | 1 | 4 | | 1996 | 7 | 0 | 7 | | 1997 | 5 | 0 | 5 | | 1998 | 3 | 0 | 3 | | 1999 | 3 | 0 | 3 | | 2000 | 12 | 0 | 12 | | 2001 | 13 | 2 | 15 | | 2002 | 14 | 0 | 14 | | 2003 | 11 | 0 | 11 | | 2004 | 9 | 4 | 13 | | 2005 | 8 | 1 | 9 | | 2006 | 14 | 1 | 15 | | 2007 | 10 | 1 | 11 | | 2008 | 6 | 0 | 6 | | 2009 | 4 | 2 | 6 | | 2010 | 7 | 1 | 8 | | 2011 | 6 | 0 | 6 | | 2012 | 4 | 0 | 4 | | 2013 | 11 | 1 | 12 | | 2014 | 6 | 2 | 8 | | 2015 | 4 | 1 | 5 | | 2016 | 3 | 0 | 3 | | 2017 | 1 | 2 | 3 | | 2018 | 3 | 0 | 3 | | 2019 | 5 | 1 | 6 | | 2020 | 1 | 1 | 2 | | 2021 | 5 | 0 | 5 |
To return to the timeline, click here.
Below are the most recent publications written about "Herpesvirus 1, Human" by people in Profiles.
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van Gent M, Chiang JJ, Muppala S, Chiang C, Azab W, Kattenhorn L, Knipe DM, Osterrieder N, Gack MU. The US3 Kinase of Herpes Simplex Virus Phosphorylates the RNA Sensor RIG-I To Suppress Innate Immunity. J Virol. 2022 02 23; 96(4):e0151021.
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Liu X, Acharya D, Krawczyk E, Kangas C, Gack MU, He B. Herpesvirus-mediated stabilization of ICP0 expression neutralizes restriction by TRIM23. Proc Natl Acad Sci U S A. 2021 12 21; 118(51).
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Bhutta MS, Sausen DG, Reed KM, Gallo ES, Hair PS, Lassiter BP, Krishna NK, Cunnion KM, Borenstein R. Peptide Inhibitor of Complement C1, RLS-0071, Reduces Zosteriform Spread of Herpes Simplex Virus Type 1 Skin Infection and Promotes Survival in Infected Mice. Viruses. 2021 07 22; 13(8).
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Liu X, Ma Y, Voss K, van Gent M, Chan YK, Gack MU, Gale M, He B. The herpesvirus accessory protein ?134.5 facilitates viral replication by disabling mitochondrial translocation of RIG-I. PLoS Pathog. 2021 03; 17(3):e1009446.
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Bhutta MS, Shechter O, Gallo ES, Martin SD, Jones E, Doncel GF, Borenstein R. Ginkgolic Acid Inhibits Herpes Simplex Virus Type 1 Skin Infection and Prevents Zosteriform Spread in Mice. Viruses. 2021 Jan 09; 13(1).
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Harrington KJ, Kong A, Mach N, Chesney JA, Fernandez BC, Rischin D, Cohen EEW, Radcliffe HS, Gumuscu B, Cheng J, Snyder W, Siu LL. Talimogene Laherparepvec and Pembrolizumab in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (MASTERKEY-232): A Multicenter, Phase 1b Study. Clin Cancer Res. 2020 10 01; 26(19):5153-5161.
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Zhou X, Wang L, Zou W, Chen X, Roizman B, Zhou GG. hnRNPA2B1 Associated with Recruitment of RNA into Exosomes Plays a Key Role in Herpes Simplex Virus 1 Release from Infected Cells. J Virol. 2020 06 16; 94(13).
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Huang R, Wu J, Zhou X, Jiang H, Guoying Zhou G, Roizman B. Herpes Simplex Virus 1 MicroRNA miR-H28 Exported to Uninfected Cells in Exosomes Restricts Cell-to-Cell Virus Spread by Inducing Gamma Interferon mRNA. J Virol. 2019 11 01; 93(21).
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Liu X, Matrenec R, Gack MU, He B. Disassembly of the TRIM23-TBK1 Complex by the Us11 Protein of Herpes Simplex Virus 1 Impairs Autophagy. J Virol. 2019 09 01; 93(17).
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Totsch SK, Schlappi C, Kang KD, Ishizuka AS, Lynn GM, Fox B, Beierle EA, Whitley RJ, Markert JM, Gillespie GY, Bernstock JD, Friedman GK. Oncolytic herpes simplex virus immunotherapy for brain tumors: current pitfalls and emerging strategies to overcome therapeutic resistance. Oncogene. 2019 08; 38(34):6159-6171.
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