 Interleukin-10
"Interleukin-10" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine produced by a variety of cell types, including T-LYMPHOCYTES; MONOCYTES; DENDRITIC CELLS; and EPITHELIAL CELLS that exerts a variety of effects on immunoregulation and INFLAMMATION. Interleukin-10 combines with itself to form a homodimeric molecule that is the biologically active form of the protein.
| Descriptor ID |
D016753
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| MeSH Number(s) |
D12.644.276.374.465.510 D12.776.467.374.465.510 D23.529.374.465.510
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| Concept/Terms |
Interleukin-10- Interleukin-10
- Interleukin 10
- IL10
- IL-10
- CSIF-10
- Cytokine Synthesis Inhibitory Factor
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Below are MeSH descriptors whose meaning is more general than "Interleukin-10".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-10".
This graph shows the total number of publications written about "Interleukin-10" by people in this website by year, and whether "Interleukin-10" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 2 | 3 | | 1995 | 2 | 1 | 3 | | 1996 | 1 | 1 | 2 | | 1997 | 1 | 2 | 3 | | 1998 | 2 | 3 | 5 | | 1999 | 2 | 1 | 3 | | 2000 | 2 | 0 | 2 | | 2001 | 1 | 1 | 2 | | 2002 | 1 | 4 | 5 | | 2003 | 1 | 4 | 5 | | 2004 | 0 | 4 | 4 | | 2005 | 0 | 2 | 2 | | 2006 | 0 | 1 | 1 | | 2007 | 2 | 3 | 5 | | 2008 | 0 | 2 | 2 | | 2009 | 2 | 2 | 4 | | 2010 | 2 | 1 | 3 | | 2011 | 0 | 6 | 6 | | 2012 | 4 | 4 | 8 | | 2013 | 3 | 2 | 5 | | 2014 | 1 | 3 | 4 | | 2015 | 4 | 5 | 9 | | 2016 | 1 | 3 | 4 | | 2017 | 2 | 2 | 4 | | 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interleukin-10" by people in Profiles.
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Zorina-Lichtenwalter K, Parisien M, Diatchenko L. Genetic studies of human neuropathic pain conditions: a review. Pain. 2018 03; 159(3):583-594.
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Pierre JF, Hinterleitner R, Bouziat R, Hubert NA, Leone V, Miyoshi J, Jabri B, Chang EB. Dietary antioxidant micronutrients alter mucosal inflammatory risk in a murine model of genetic and microbial susceptibility. J Nutr Biochem. 2018 04; 54:95-104.
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Ogasawara N, Poposki JA, Klingler AI, Tan BK, Weibman AR, Hulse KE, Stevens WW, Peters AT, Grammer LC, Schleimer RP, Welch KC, Smith SS, Conley DB, Raviv JR, Soroosh P, Akbari O, Himi T, Kern RC, Kato A. IL-10, TGF-ß, and glucocorticoid prevent the production of type 2 cytokines in human group 2 innate lymphoid cells. J Allergy Clin Immunol. 2018 03; 141(3):1147-1151.e8.
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Wang Y, Lin F, Zhu X, Leone VA, Dalal S, Tao Y, Messer JS, Chang EB. Distinct roles of intracellular heat shock protein 70 in maintaining gastrointestinal homeostasis. Am J Physiol Gastrointest Liver Physiol. 2018 02 01; 314(2):G164-G178.
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Chong AS, Khiew SH. Transplantation tolerance: don't forget about the B cells. Clin Exp Immunol. 2017 08; 189(2):171-180.
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Alferink J, Specht S, Arends H, Schumak B, Schmidt K, Ruland C, Lundt R, Kemter A, Dlugos A, Kuepper JM, Poppensieker K, Findeiss M, Albayram Ö, Otte DM, Marazzi J, Gertsch J, Förster I, Maier W, Scheu S, Hoerauf A, Zimmer A. Cannabinoid Receptor 2 Modulates Susceptibility to Experimental Cerebral Malaria through a CCL17-dependent Mechanism. J Biol Chem. 2016 09 09; 291(37):19517-31.
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Ward MA, Pierre JF, Leal RF, Huang Y, Shogan B, Dalal SR, Weber CR, Leone VA, Musch MW, An GC, Rao MC, Rubin DT, Raffals LE, Antonopoulos DA, Sogin ML, Hyman NH, Alverdy JC, Chang EB. Insights into the pathogenesis of ulcerative colitis from a murine model of stasis-induced dysbiosis, colonic metaplasia, and genetic susceptibility. Am J Physiol Gastrointest Liver Physiol. 2016 06 01; 310(11):G973-88.
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Benakis C, Brea D, Caballero S, Faraco G, Moore J, Murphy M, Sita G, Racchumi G, Ling L, Pamer EG, Iadecola C, Anrather J. Commensal microbiota affects ischemic stroke outcome by regulating intestinal ?d T cells. Nat Med. 2016 05; 22(5):516-23.
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Quan S, Sheng JR, Abraham PM, Soliven B. Regulatory T and B lymphocytes in a spontaneous autoimmune polyneuropathy. Clin Exp Immunol. 2016 Apr; 184(1):50-61.
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Sheng JR, Quan S, Soliven B. IL-10 derived from CD1dhiCD5? B cells regulates experimental autoimmune myasthenia gravis. J Neuroimmunol. 2015 Dec 15; 289:130-8.
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