"Interleukin-7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine produced by bone marrow stromal cells that promotes the growth of B-LYMPHOCYTE precursors and is co-mitogenic with INTERLEUKIN-2 for mature T-LYMPHOCYTE activation.
| Descriptor ID |
D015851
|
| MeSH Number(s) |
D12.644.276.374.465.246 D12.776.467.374.465.224 D23.529.374.465.246
|
| Concept/Terms |
Interleukin-7- Interleukin-7
- Interleukin 7
- IL7
- Lymphopoietin-1
- Lymphopoietin 1
- IL-7
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-7".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-7".
This graph shows the total number of publications written about "Interleukin-7" by people in this website by year, and whether "Interleukin-7" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 2 | 2 |
| 1995 | 0 | 1 | 1 |
| 1996 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 1 | 2 |
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 1 | 2 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 2 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 2 | 0 | 2 |
| 2012 | 1 | 1 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 3 | 3 |
| 2016 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interleukin-7" by people in Profiles.
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Engineered IL-7 synergizes with IL-12 immunotherapy to prevent T cell exhaustion and promote memory without exacerbating toxicity. Sci Adv. 2023 12; 9(48):eadh9879.
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IL-7 expands lymphocyte populations and enhances immune responses to sipuleucel-T in patients with metastatic castration-resistant prostate cancer (mCRPC). J Immunother Cancer. 2021 08; 9(8).
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Control of Early B Cell Development by the RNA N6-Methyladenosine Methylation. Cell Rep. 2020 06 30; 31(13):107819.
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Tumor-induced stromal reprogramming drives lymph node transformation. Nat Immunol. 2016 09; 17(9):1118-27.
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Targeting bone marrow lymphoid niches in acute lymphoblastic leukemia. Leuk Res. 2015 Dec; 39(12):1437-42.
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Histone reader BRWD1 targets and restricts recombination to the Igk locus. Nat Immunol. 2015 Oct; 16(10):1094-103.
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The transcription factor lymphoid enhancer factor 1 controls invariant natural killer T cell expansion and Th2-type effector differentiation. J Exp Med. 2015 May 04; 212(5):793-807.
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Basal NF-?B controls IL-7 responsiveness of quiescent naïve T cells. Proc Natl Acad Sci U S A. 2014 May 20; 111(20):7397-402.
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Dose-adjusted EPOCH-rituximab combined with fludarabine provides an effective bridge to reduced-intensity allogeneic hematopoietic stem-cell transplantation in patients with lymphoid malignancies. J Clin Oncol. 2012 Mar 10; 30(8):830-6.
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A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation. Nat Immunol. 2012 Jan 22; 13(3):300-7.