"Apoptosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
Descriptor ID |
D017209
|
MeSH Number(s) |
G04.146.160
|
Concept/Terms |
Apoptosis- Apoptosis
- Programmed Cell Death, Type I
|
Below are MeSH descriptors whose meaning is more general than "Apoptosis".
Below are MeSH descriptors whose meaning is more specific than "Apoptosis".
This graph shows the total number of publications written about "Apoptosis" by people in this website by year, and whether "Apoptosis" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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1994 | 4 | 3 | 7 |
1995 | 5 | 1 | 6 |
1996 | 13 | 4 | 17 |
1997 | 22 | 8 | 30 |
1998 | 26 | 15 | 41 |
1999 | 23 | 10 | 33 |
2000 | 25 | 23 | 48 |
2001 | 37 | 22 | 59 |
2002 | 34 | 29 | 63 |
2003 | 45 | 32 | 77 |
2004 | 38 | 48 | 86 |
2005 | 25 | 25 | 50 |
2006 | 22 | 44 | 66 |
2007 | 22 | 33 | 55 |
2008 | 18 | 33 | 51 |
2009 | 13 | 38 | 51 |
2010 | 12 | 46 | 58 |
2011 | 13 | 34 | 47 |
2012 | 18 | 41 | 59 |
2013 | 14 | 41 | 55 |
2014 | 14 | 44 | 58 |
2015 | 13 | 33 | 46 |
2016 | 8 | 41 | 49 |
2017 | 5 | 25 | 30 |
2018 | 12 | 29 | 41 |
2019 | 4 | 13 | 17 |
2020 | 3 | 18 | 21 |
2021 | 1 | 25 | 26 |
2022 | 2 | 5 | 7 |
2023 | 0 | 9 | 9 |
2024 | 1 | 5 | 6 |
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Below are the most recent publications written about "Apoptosis" by people in Profiles.
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Exosome Therapy: A Novel Approach for Enhancing Estrogen Levels in Perimenopause. Int J Mol Sci. 2024 Jun 27; 25(13).
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MerTK Drives Proliferation and Metastatic Potential in Triple-Negative Breast Cancer. Int J Mol Sci. 2024 May 08; 25(10).
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Fertility protection: a novel approach using pretreatment with mesenchymal stem cell exosomes to prevent chemotherapy-induced ovarian damage in a mouse model. Am J Obstet Gynecol. 2024 Jul; 231(1):111.e1-111.e18.
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The potent paracrine effect of umbilical cord mesenchymal stem cells mediates mitochondrial quality control to restore chemotherapy-induced damage in ovarian granulosa cells. Biomed Pharmacother. 2024 Mar; 172:116263.
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Immunogenic Bifunctional Nanoparticle Suppresses Programmed Cell Death-Ligand 1 in Cancer and Dendritic Cells to Enhance Adaptive Immunity and Chemo-Immunotherapy. ACS Nano. 2024 Feb 13; 18(6):5152-5166.
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Ruthenium-dihydroartemisinin complex: a promising new compound for colon cancer prevention via G1 cell cycle arrest, apoptotic induction, and adaptive immune regulation. Cancer Chemother Pharmacol. 2024 May; 93(5):411-425.
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Effect of antibiotic monensin on cell proliferation and IGF1R signaling pathway in human colorectal cancer cells. Ann Med. 2023 12; 55(1):954-964.
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A novel triptolide analog downregulates NF-?B and induces mitochondrial apoptosis pathways in human pancreatic cancer. Elife. 2023 Oct 25; 12.
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Apoptosis in mesenchymal stromal cells activates an immunosuppressive secretome predicting clinical response in Crohn's disease. Mol Ther. 2023 Dec 06; 31(12):3531-3544.
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Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development. J Am Heart Assoc. 2023 09 19; 12(18):e029683.