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Brandon Faubert

TitleAssistant Professor
InstitutionUniversity of Chicago
DepartmentMedicine-Hematology and Oncology
AddressChicago IL 60637
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    Collapse Overview 
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    The primary research interest of the Faubert laboratory is investigating how metabolic reprogramming – alterations of metabolic flux in malignant cells – supports cancer cell survival and growth. We have extensive experience in measuring metabolism in vitro and in vivo, including measuring tumor metabolism intra-operatively in patients. The laboratory utilizes a series of mass spectrometry platforms to provide comprehensive views of metabolic pathways in biological systems. We use a variety of methods to assess metabolism, including isotope tracing (13C, 2H, etc.), metabolomics and metabolic flux to dissect the metabolic programs that underlie these malignant phenotypes. We complement these approaches with molecular imaging techniques to monitor metabolic states of tumor metabolism in vivo, in order to understand the breadth of metabolic diversity in cancer. Emerging work from the lab explores the metabolic alterations that occur during the metastatic cascade, and the tumor metabolism that results unique microenvironments.

    Collapse Biography 
    Collapse education and training
    McGill University, MontrealPhD2015Physiology
    UT Southwestern, DallasPostdoc2021Cancer Metabolism

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Feng Q, Bennett Z, Grichuk A, Pantoja R, Huang T, Faubert B, Huang G, Chen M, DeBerardinis RJ, Sumer BD, Gao J. Severely polarized extracellular acidity around tumour cells. Nat Biomed Eng. 2024 Mar 04. PMID: 38438799.
      Citations:    Fields:    
    2. Miller JW, Faubert BM, Mathews TP, Waters JK, DeBerardinis RJ, Kernstine KH. Metabolic signatures of thymomas: potential biomarkers and treatment targets. Eur J Cardiothorac Surg. 2024 Feb 01; 65(2). PMID: 38011656; PMCID: PMC10882262.
      Citations: 1     Fields:    Translation:Humans
    3. Fan H, Xia S, Xiang J, Li Y, Ross MO, Lim SA, Yang F, Tu J, Xie L, Dougherty U, Zhang FQ, Zheng Z, Zhang R, Wu R, Dong L, Su R, Chen X, Althaus T, Riedell PA, Jonker PB, Muir A, Lesinski GB, Rafiq S, Dhodapkar MV, Stock W, Odenike O, Patel AA, Opferman J, Tsuji T, Matsuzaki J, Shah H, Faubert B, Elf SE, Layden B, Bissonnette BM, He YY, Kline J, Mao H, Odunsi K, Gao X, Chi H, He C, Chen J. Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity. Nature. 2023 Nov; 623(7989):1034-1043. PMID: 37993715; PMCID: PMC10686835.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    4. Bartman CR, Faubert B, Rabinowitz JD, DeBerardinis RJ. Metabolic pathway analysis using stable isotopes in patients with cancer. Nat Rev Cancer. 2023 Dec; 23(12):863-878. PMID: 37907620.
      Citations: 3     Fields:    Translation:HumansCells
    5. Mukherjee A, Bezwada D, Greco F, Zandbergen M, Shen T, Chiang CY, Tasdemir M, Fahrmann J, Grapov D, La Frano MR, Vu HS, Faubert B, Newman JW, McDonnell LA, Nezi L, Fiehn O, DeBerardinis RJ, Lengyel E. Adipocytes reprogram cancer cell metabolism by diverting glucose towards glycerol-3-phosphate thereby promoting metastasis. Nat Metab. 2023 09; 5(9):1563-1577. PMID: 37653041.
      Citations: 1     Fields:    Translation:HumansCells
    6. Wu Z, Bezwada D, Harris RC, Pan C, Nguyen PT, Faubert B, Cai L, Cai F, Vu HS, Chen H, Sandoval MM, Do D, Gu W, Zhang Y, Ko B, Brooks B, Kelekar S, Zhang Y, Zacharias LG, Oaxaca KC, Mathews TP, Garcia-Bermudez J, Ni M, DeBerardinis RJ. Electron transport chain inhibition increases cellular dependence on purine transport and salvage. bioRxiv. 2023 May 11. PMID: 37214913; PMCID: PMC10197673.
      Citations:    
    7. Kaushik AK, Tarangelo A, Boroughs LK, Zhang Y, Wu CY, Li X, Ahumada K, Chiang JC, Do QN, Yong C, Rosales T, Rao AD, Faubert B, Pachnis P, Zacharias LG, Vu H, Cai F, Mathews TP, Genovese G, Slusher BS, Sun X, Merritt M, DeBerardinis RJ, Ragavan M, Tcheuyap VT, Saatchi F, Stevens C, Kapur P, Brugarolas J. In vivo characterization of glutamine metabolism identifies therapeutic targets in clear cell renal cell carcinoma. Sci Adv. 2022 12 16; 8(50):eabp8293. PMID: 36525494; PMCID: PMC9757752.
      Citations: 10     Fields:    Translation:HumansAnimals
    8. Pachnis P, Wu Z, Faubert B, Tasdogan A, Gu W, Shelton S, Solmonson A, Rao AD, Kaushik AK, Rogers TJ, Ubellacker JM, LaVigne CA, Yang C, Ko B, Ramesh V, Sudderth J, Zacharias LG, Martin-Sandoval MS, Do D, Mathews TP, Zhao Z, Mishra P, Morrison SJ, DeBerardinis RJ. In vivo isotope tracing reveals a requirement for the electron transport chain in glucose and glutamine metabolism by tumors. Sci Adv. 2022 09 02; 8(35):eabn9550. PMID: 36044570; PMCID: PMC9432826.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    9. Kaymak I, Duimstra LR, Ma EH, Longo J, Dahabieh MS, Faubert B, Oswald BM, Watson MJ, Kitchen-Goosen SM, DeCamp LM, Compton SE, Fu Z, DeBerardinis RJ, Williams KS, Sheldon RD, Jones RG, Luda KM. Carbon source availability drives nutrient utilization in CD8+ T cells. Cell Metab. 2022 09 06; 34(9):1298-1311.e6. PMID: 35981545; PMCID: PMC10068808.
      Citations: 24     Fields:    Translation:Cells
    10. Zhang R, Chen D, Fan H, Wu R, Tu J, Zhang FQ, Wang M, Zheng H, Qu CK, Elf SE, Faubert B, He YY, Bissonnette MB, Gao X, DeBerardinis RJ, Chen J. Cellular signals converge at the NOX2-SHP-2 axis to induce reductive carboxylation in cancer cells. Cell Chem Biol. 2022 07 21; 29(7):1200-1208.e6. PMID: 35429459; PMCID: PMC9308720.
      Citations: 2     Fields:    Translation:Cells
    11. Gao X, Liu Y, Li Y, Fan H, Wu R, Zhang R, Faubert B, He YY, Bissonnette MB, Xia S, Chen D, Mao H, Boggon TJ, Chen J. Lyso-PAF, a biologically inactive phospholipid, contributes to RAF1 activation. Mol Cell. 2022 06 02; 82(11):1992-2005.e9. PMID: 35417664; PMCID: PMC9177793.
      Citations: 2     Fields:    
    12. Solmonson A, Faubert B, Gu W, Rao A, Cowdin MA, Menendez-Montes I, Kelekar S, Rogers TJ, Pan C, Guevara G, Tarangelo A, Zacharias LG, Martin-Sandoval MS, Do D, Pachnis P, Dumesnil D, Mathews TP, Tasdogan A, Pham A, Cai L, Zhao Z, Ni M, Cleaver O, Sadek HA, Morrison SJ, DeBerardinis RJ. Compartmentalized metabolism supports midgestation mammalian development. Nature. 2022 04; 604(7905):349-353. PMID: 35388219; PMCID: PMC9007737.
      Citations: 33     Fields:    Translation:AnimalsCells
    13. Suh EH, Geraldes CFGC, Chirayil S, Faubert B, Ayala R, DeBerardinis RJ, Sherry AD. Detection of glucose-derived D- and L-lactate in cancer cells by the use of a chiral NMR shift reagent. Cancer Metab. 2021 Nov 06; 9(1):38. PMID: 34742347; PMCID: PMC8571830.
      Citations: 3     
    14. Faubert B, Tasdogan A, Morrison SJ, Mathews TP, DeBerardinis RJ. Stable isotope tracing to assess tumor metabolism in vivo. Nat Protoc. 2021 11; 16(11):5123-5145. PMID: 34535790; PMCID: PMC9274147.
      Citations: 21     Fields:    Translation:Animals
    15. Johnston K, Pachnis P, Tasdogan A, Faubert B, Zacharias LG, Vu HS, Rodgers-Augustyniak L, Johnson A, Huang F, Ricciardo S, Zhao Z, Mathews TP, Watt T, Leavey P, DeBerardinis RJ. Isotope tracing reveals glycolysis and oxidative metabolism in childhood tumors of multiple histologies. Med (N Y). 2021 04 09; 2(4):395-410. PMID: 33860280; PMCID: PMC8045768.
      Citations: 16     Fields:    Translation:HumansCellsCTClinical Trials
    16. Kim J, Lee HM, Cai F, Ko B, Yang C, Lieu EL, Muhammad N, Rhyne S, Li K, Haloul M, Gu W, Faubert B, Kaushik AK, Cai L, Kasiri S, Marriam U, Nham K, Girard L, Wang H, Sun X, Kim J, Minna JD, Unsal-Kacmaz K, DeBerardinis RJ. The hexosamine biosynthesis pathway is a targetable liability in KRAS/LKB1 mutant lung cancer. Nat Metab. 2020 12; 2(12):1401-1412. PMID: 33257855; PMCID: PMC7744327.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    17. Gerber DE, Putnam WC, Fattah FJ, Kernstine KH, Brekken RA, Pedrosa I, Skelton R, Saltarski JM, Lenkinski RE, Leff RD, Ahn C, Padmanabhan C, Chembukar V, Kasiri S, Kallem RR, Subramaniyan I, Yuan Q, Do QN, Xi Y, Reznik SI, Pelosof L, Faubert B, DeBerardinis RJ, Kim J. Concentration-dependent Early Antivascular and Antitumor Effects of Itraconazole in Non-Small Cell Lung Cancer. Clin Cancer Res. 2020 11 15; 26(22):6017-6027. PMID: 32847935; PMCID: PMC7669726.
      Citations: 12     Fields:    Translation:HumansCTClinical Trials
    18. Faubert B, Solmonson A, DeBerardinis RJ. Metabolic reprogramming and cancer progression. Science. 2020 04 10; 368(6487). PMID: 32273439; PMCID: PMC7227780.
      Citations: 621     Fields:    Translation:HumansAnimals
    19. Tasdogan A, Faubert B, Ramesh V, Ubellacker JM, Shen B, Solmonson A, Murphy MM, Gu Z, Gu W, Martin M, Kasitinon SY, Vandergriff T, Mathews TP, Zhao Z, Schadendorf D, DeBerardinis RJ, Morrison SJ. Metabolic heterogeneity confers differences in melanoma metastatic potential. Nature. 2020 01; 577(7788):115-120. PMID: 31853067; PMCID: PMC6930341.
      Citations: 193     Fields:    Translation:HumansAnimalsCells
    20. Kernstine KH, Faubert B, Do QN, Rogers TJ, Hensley CT, Cai L, Torrealba J, Oliver D, Wachsmann JW, Lenkinski RE, Malloy CR, Deberardinis RJ. Does Tumor FDG-PET Avidity Represent Enhanced Glycolytic Metabolism in Non-Small Cell Lung Cancer? Ann Thorac Surg. 2020 04; 109(4):1019-1025. PMID: 31846640; PMCID: PMC7370816.
      Citations: 11     Fields:    Translation:HumansCellsCTClinical Trials
    21. Luengo A, Abbott KL, Davidson SM, Hosios AM, Faubert B, Chan SH, Freinkman E, Zacharias LG, Mathews TP, Clish CB, DeBerardinis RJ, Lewis CA, Vander Heiden MG. Reactive metabolite production is a targetable liability of glycolytic metabolism in lung cancer. Nat Commun. 2019 12 06; 10(1):5604. PMID: 31811141; PMCID: PMC6898239.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    22. Ma EH, Verway MJ, Johnson RM, Roy DG, Steadman M, Hayes S, Williams KS, Sheldon RD, Samborska B, Kosinski PA, Kim H, Griss T, Faubert B, Condotta SA, Krawczyk CM, DeBerardinis RJ, Stewart KM, Richer MJ, Chubukov V, Roddy TP, Jones RG. Metabolic Profiling Using Stable Isotope Tracing Reveals Distinct Patterns of Glucose Utilization by Physiologically Activated CD8+ T Cells. Immunity. 2019 11 19; 51(5):856-870.e5. PMID: 31747582.
      Citations: 155     Fields:    Translation:AnimalsCells
    23. Chen PH, Cai L, Huffman K, Yang C, Kim J, Faubert B, Boroughs L, Ko B, Sudderth J, McMillan EA, Girard L, Chen D, Peyton M, Shields MD, Yao B, Shames DS, Kim HS, Timmons B, Sekine I, Britt R, Weber S, Byers LA, Heymach JV, Chen J, White MA, Minna JD, Xiao G, DeBerardinis RJ. Metabolic Diversity in Human Non-Small Cell Lung Cancer Cells. Mol Cell. 2019 12 05; 76(5):838-851.e5. PMID: 31564558; PMCID: PMC6898782.
      Citations: 80     Fields:    Translation:HumansCells
    24. Hsieh MH, Choe JH, Gadhvi J, Kim YJ, Arguez MA, Palmer M, Gerold H, Nowak C, Do H, Mazambani S, Knighton JK, Cha M, Goodwin J, Kang MK, Jeong JY, Lee SY, Faubert B, Xuan Z, Abel ED, Scafoglio C, Shackelford DB, Minna JD, Singh PK, Shulaev V, Bleris L, Hoyt K, Kim J, Inoue M, DeBerardinis RJ, Kim TH, Kim JW. p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas. Cell Rep. 2019 08 13; 28(7):1860-1878.e9. PMID: 31412252; PMCID: PMC7048935.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    25. Faubert B, DeBerardinis RJ, Minna JD. AIF: an acquired metabolic liability in lung cancer. Cell Res. 2019 08; 29(8):607-608. PMID: 31267018; PMCID: PMC6796866.
      Citations: 1     Fields:    Translation:HumansCells
    26. Kim J, Hu Z, Cai L, Li K, Choi E, Faubert B, Bezwada D, Rodriguez-Canales J, Villalobos P, Lin YF, Ni M, Huffman KE, Girard L, Byers LA, Unsal-Kacmaz K, Heymach JV, Wauters E, Vansteenkiste J, Castrillon DH, Chen BPC, Wistuba I, Lambrechts D, Xu J, Minna JD, DeBerardinis RJ, Peña CG. Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells. Nature. 2019 May; 569(7756):E4. PMID: 31043737.
      Citations: 2     Fields:    
    27. Ni M, Solmonson A, Pan C, Yang C, Li D, Notzon A, Cai L, Guevara G, Zacharias LG, Faubert B, Vu HS, Jiang L, Ko B, Morales NM, Pei J, Rakheja D, Grishin NV, McDonald JG, Gotway GK, McNutt MC, Pascual JM, DeBerardinis RJ, Vale G. Functional Assessment of Lipoyltransferase-1 Deficiency in Cells, Mice, and Humans. Cell Rep. 2019 04 30; 27(5):1376-1386.e6. PMID: 31042466; PMCID: PMC7351313.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    28. Vriens K, Christen S, Parik S, Broekaert D, Yoshinaga K, Talebi A, Dehairs J, Escalona-Noguero C, Schmieder R, Cornfield T, Charlton C, Rossi M, Rinaldi G, Orth MF, Boon R, Kerstens A, Kwan SY, Faubert B, Kopitz CC, Chen T, Fernandez-Garcia J, Schmitz AA, Steigemann P, Van Ginderachter JA, Gotoh N, Wong KK, Verfaillie C, Derua R, Munck S, Yuneva M, Beretta L, DeBerardinis RJ, Swinnen JV, Hodson L, Cassiman D, Verslype C, Christian S, Fendt SM, Romero-Pérez L, Méndez-Lucas A, Duarte JAG, Najimi M, Hägebarth A, Sokal E, Grünewald S, Grünewald TGP. Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity. Nature. 2019 02; 566(7744):403-406. PMID: 30728499; PMCID: PMC6390935.
      Citations: 170     Fields:    Translation:HumansAnimalsCells
    29. Faubert B, Li KY, Cai L, Hensley CT, Kim J, Zacharias LG, Yang C, Do QN, Doucette S, Burguete D, Li H, Huet G, Yuan Q, Wigal T, Butt Y, Ni M, Torrealba J, Oliver D, Lenkinski RE, Malloy CR, Wachsmann JW, Young JD, Kernstine K, DeBerardinis RJ. Lactate Metabolism in Human Lung Tumors. Cell. 2017 Oct 05; 171(2):358-371.e9. PMID: 28985563; PMCID: PMC5684706.
      Citations: 544     Fields:    Translation:HumansAnimalsCells
    30. Rabinovitch RC, Samborska B, Faubert B, Ma EH, Gravel SP, Andrzejewski S, Raissi TC, Pause A, St-Pierre J, Jones RG. AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species. Cell Rep. 2017 Oct 03; 21(1):1-9. PMID: 28978464.
      Citations: 223     Fields:    Translation:HumansAnimalsCells
    31. Kim J, Hu Z, Cai L, Li K, Choi E, Faubert B, Bezwada D, Rodriguez-Canales J, Villalobos P, Lin YF, Ni M, Huffman KE, Girard L, Byers LA, Unsal-Kacmaz K, Heymach JV, Wauters E, Vansteenkiste J, Castrillon DH, Chen BPC, Wistuba I, Lambrechts D, Xu J, Minna JD, DeBerardinis RJ, Peña CG. CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells. Nature. 2017 06 01; 546(7656):168-172. PMID: 28538732; PMCID: PMC5472349.
      Citations: 153     Fields:    Translation:HumansAnimalsCells
    32. Faubert B, DeBerardinis RJ. Analyzing Tumor Metabolism In Vivo. Annual Review of Cancer Biology. 2016; 1(1):99-117. View Publication.
    33. Hensley CT, Faubert B, Yuan Q, Lev-Cohain N, Jin E, Kim J, Jiang L, Ko B, Skelton R, Loudat L, Wodzak M, Klimko C, McMillan E, Butt Y, Ni M, Oliver D, Torrealba J, Malloy CR, Kernstine K, Lenkinski RE, DeBerardinis RJ. Metabolic Heterogeneity in Human Lung Tumors. Cell. 2016 Feb 11; 164(4):681-94. PMID: 26853473; PMCID: PMC4752889.
      Citations: 532     Fields:    Translation:HumansCells
    34. Griss T, Vincent EE, Egnatchik R, Chen J, Ma EH, Faubert B, Viollet B, DeBerardinis RJ, Jones RG. Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis. PLoS Biol. 2015 Dec; 13(12):e1002309. PMID: 26625127; PMCID: PMC4666657.
      Citations: 118     Fields:    Translation:HumansAnimalsCells
    35. Bott AJ, Peng IC, Fan Y, Faubert B, Zhao L, Li J, Neidler S, Sun Y, Jaber N, Krokowski D, Lu W, Pan JA, Powers S, Rabinowitz J, Hatzoglou M, Murphy DJ, Jones R, Wu S, Girnun G, Zong WX. Oncogenic Myc Induces Expression of Glutamine Synthetase through Promoter Demethylation. Cell Metab. 2015 Dec 01; 22(6):1068-77. PMID: 26603296; PMCID: PMC4670565.
      Citations: 125     Fields:    Translation:HumansAnimalsCells
    36. Pereira S, Park E, Moore J, Faubert B, Breen DM, Oprescu AI, Nahle A, Kwan D, Giacca A, Tsiani E. Resveratrol prevents insulin resistance caused by short-term elevation of free fatty acids in vivo. Appl Physiol Nutr Metab. 2015 Nov; 40(11):1129-36. PMID: 26455923.
      Citations: 13     Fields:    Translation:AnimalsCells
    37. Fu A, Robitaille K, Faubert B, Reeks C, Dai XQ, Hardy AB, Sankar KS, Ogrel S, Al-Dirbashi OY, Rocheleau JV, Wheeler MB, MacDonald PE, Jones R, Screaton RA. LKB1 couples glucose metabolism to insulin secretion in mice. Diabetologia. 2015 Jul; 58(7):1513-22. PMID: 25874445.
      Citations: 16     Fields:    Translation:AnimalsCells
    38. Yan M, Gingras MC, Dunlop EA, Dupuy F, Jalali Z, Possik E, Coull BJ, Kharitidi D, Dydensborg AB, Faubert B, Kamps M, Sabourin S, Preston RS, Davies DM, Roughead T, van Steensel MA, Jones R, Tee AR, Pause A, Nouët Y, Chotard L. The tumor suppressor folliculin regulates AMPK-dependent metabolic transformation. J Clin Invest. 2014 Jun; 124(6):2640-50. PMID: 24762438; PMCID: PMC4038567.
      Citations: 77     Fields:    Translation:AnimalsCells
    39. Faubert B, Vincent EE, Griss T, Samborska B, Izreig S, Svensson RU, Mamer OA, Avizonis D, Shackelford DB, Shaw RJ, Jones RG. Loss of the tumor suppressor LKB1 promotes metabolic reprogramming of cancer cells via HIF-1a. Proc Natl Acad Sci U S A. 2014 Feb 18; 111(7):2554-9. PMID: 24550282; PMCID: PMC3932920.
      Citations: 136     Fields:    Translation:HumansAnimalsCells
    40. Faubert B, Vincent EE, Poffenberger MC, Jones RG. The AMP-activated protein kinase (AMPK) and cancer: many faces of a metabolic regulator. Cancer Lett. 2015 Jan 28; 356(2 Pt A):165-70. PMID: 24486219.
      Citations: 154     Fields:    Translation:HumansCells
    41. Hiller K, McGuirk S, Gravel SP, Deblois G, Papadopoli DJ, Faubert B, Wegner A, Avizonis D, Akavia UD, Jones RG, Giguère V, St-Pierre J. PGC-1a supports glutamine metabolism in breast cancer. Cancer Metab. 2013 Dec 05; 1(1):22. PMID: 24304688; PMCID: PMC4178216.
      Citations: 76     
    42. van der Windt GJ, O'Sullivan D, Everts B, Huang SC, Buck MD, Curtis JD, Chang CH, Smith AM, Ai T, Faubert B, Jones RG, Pearce EJ, Pearce EL. CD8 memory T cells have a bioenergetic advantage that underlies their rapid recall ability. Proc Natl Acad Sci U S A. 2013 Aug 27; 110(35):14336-41. PMID: 23940348; PMCID: PMC3761631.
      Citations: 264     Fields:    Translation:AnimalsCells
    43. Chang CH, Curtis JD, Maggi LB, Faubert B, Villarino AV, O'Sullivan D, Huang SC, van der Windt GJ, Blagih J, Qiu J, Weber JD, Pearce EJ, Jones RG, Pearce EL. Posttranscriptional control of T cell effector function by aerobic glycolysis. Cell. 2013 Jun 06; 153(6):1239-51. PMID: 23746840; PMCID: PMC3804311.
      Citations: 1073     Fields:    Translation:AnimalsCells
    44. Leprivier G, Remke M, Rotblat B, Dubuc A, Mateo AR, Kool M, Agnihotri S, El-Naggar A, Yu B, Somasekharan SP, Faubert B, Tognon CE, Mathers J, Thomas R, Li A, Barokas A, Kwok B, Bowden M, Smith S, Wu X, Korshunov A, Hielscher T, Northcott PA, Galpin JD, Ahern CA, Wang Y, McCabe MG, Collins VP, Jones RG, Pollak M, Delattre O, Gleave ME, Jan E, Pfister SM, Proud CG, Derry WB, Taylor MD, Sorensen PH, Bridon G. The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation. Cell. 2013 May 23; 153(5):1064-79. PMID: 23706743; PMCID: PMC4395874.
      Citations: 200     Fields:    Translation:HumansAnimalsCells
    45. Faubert B, Boily G, Izreig S, Griss T, Samborska B, Dong Z, Dupuy F, Chambers C, Fuerth BJ, Viollet B, Mamer OA, Avizonis D, DeBerardinis RJ, Siegel PM, Jones RG. AMPK is a negative regulator of the Warburg effect and suppresses tumor growth in vivo. Cell Metab. 2013 Jan 08; 17(1):113-24. PMID: 23274086; PMCID: PMC3545102.
      Citations: 433     Fields:    Translation:HumansAnimalsCells
    46. Zaugg K, Yao Y, Reilly PT, Kannan K, Kiarash R, Mason J, Huang P, Sawyer SK, Fuerth B, Faubert B, Elia A, Luo X, Nadeem V, Bungard D, Yalavarthi S, Growney JD, Wakeham A, Moolani Y, Silvester J, Ten AY, Bakker W, Tsuchihara K, Berger SL, Hill RP, Jones RG, Tsao M, Robinson MO, Thompson CB, Pan G, Mak TW, Kalliomäki T. Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress. Genes Dev. 2011 May 15; 25(10):1041-51. PMID: 21576264; PMCID: PMC3093120.
      Citations: 253     Fields:    Translation:HumansAnimalsCells
    47. Bungard D, Fuerth BJ, Zeng PY, Faubert B, Maas NL, Viollet B, Carling D, Thompson CB, Jones RG, Berger SL. Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. Science. 2010 Sep 03; 329(5996):1201-5. PMID: 20647423; PMCID: PMC3922052.
      Citations: 203     Fields:    Translation:HumansAnimalsCells
    48. Zygmunt K, Faubert B, MacNeil J, Tsiani E. Naringenin, a citrus flavonoid, increases muscle cell glucose uptake via AMPK. Biochem Biophys Res Commun. 2010 Jul 23; 398(2):178-83. PMID: 20558145.
      Citations: 58     Fields:    Translation:AnimalsCells
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