Fragile X Mental Retardation Protein
"Fragile X Mental Retardation Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A RNA-binding protein that is found predominately in the CYTOPLASM. It helps regulate GENETIC TRANSLATION in NEURONS and is absent or under-expressed in FRAGILE X SYNDROME.
| Descriptor ID |
D051860
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| MeSH Number(s) |
D12.776.157.725.061 D12.776.631.299 D12.776.664.962.124
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Fragile X Mental Retardation Protein".
Below are MeSH descriptors whose meaning is more specific than "Fragile X Mental Retardation Protein".
This graph shows the total number of publications written about "Fragile X Mental Retardation Protein" by people in this website by year, and whether "Fragile X Mental Retardation Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2019 | 2 | 0 | 2 |
| 2021 | 1 | 1 | 2 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Fragile X Mental Retardation Protein" by people in Profiles.
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FMRP phosphorylation modulates neuronal translation through YTHDF1. Mol Cell. 2023 Dec 07; 83(23):4304-4317.e8.
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Beyond Trinucleotide Repeat Expansion in Fragile X Syndrome: Rare Coding and Noncoding Variants in FMR1 and Associated Phenotypes. Genes (Basel). 2021 10 22; 12(11).
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The genetic landscape of intellectual disability and epilepsy in adults and the elderly: a systematic genetic work-up of 150 individuals. Genet Med. 2021 08; 23(8):1492-1497.
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The RNA-binding protein FMRP facilitates the nuclear export of N6-methyladenosine-containing mRNAs. J Biol Chem. 2019 12 27; 294(52):19889-19895.
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FMRP Modulates Neural Differentiation through m6A-Dependent mRNA Nuclear Export. Cell Rep. 2019 07 23; 28(4):845-854.e5.
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Diminished ovarian reserve is not observed in infertility patients with high normal CGG repeats on the fragile X mental retardation 1 (FMR1) gene. Hum Reprod. 2015 Nov; 30(11):2686-92.
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Developmental and behavioral pediatricians' attitudes toward screening for fragile X. Am J Intellect Dev Disabil. 2013 Jul; 118(4):284-93.
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Statistical inference of in vivo properties of human DNA methyltransferases from double-stranded methylation patterns. PLoS One. 2012; 7(3):e32225.
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Neuroanatomy of fragile X syndrome is associated with aberrant behavior and the fragile X mental retardation protein (FMRP). Ann Neurol. 2008 Jan; 63(1):40-51.
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Screen for expanded FMR1 alleles in patients with essential tremor. Mov Disord. 2004 Aug; 19(8):930-3.