"Cyclin B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cyclin subtype that is transported into the CELL NUCLEUS at the end of the G2 PHASE. It stimulates the G2/M phase transition by activating CDC2 PROTEIN KINASE.
| Descriptor ID |
D019926
|
| MeSH Number(s) |
D12.644.360.262.120 D12.776.167.218.120 D12.776.476.262.120
|
| Concept/Terms |
Cyclin B- Cyclin B
- Type B Cyclin
- Cyclin, Type B
- Type B Cyclins
- Cyclins, Type B
|
Below are MeSH descriptors whose meaning is more general than "Cyclin B".
Below are MeSH descriptors whose meaning is more specific than "Cyclin B".
This graph shows the total number of publications written about "Cyclin B" by people in this website by year, and whether "Cyclin B" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 1 | 2 |
| 2001 | 0 | 3 | 3 |
| 2004 | 1 | 1 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 3 | 3 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclin B" by people in Profiles.
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Cyclin E deregulation impairs mitotic progression through premature activation of Cdc25C. Cancer Res. 2010 Jun 15; 70(12):5085-95.
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Transient nutlin-3a treatment promotes endoreduplication and the generation of therapy-resistant tetraploid cells. Cancer Res. 2008 Oct 15; 68(20):8260-8.
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Stimulation of human and rat islet beta-cell proliferation with retention of function by the homeodomain transcription factor Nkx6.1. Mol Cell Biol. 2008 May; 28(10):3465-76.
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Toxoplasma gondii exploits UHRF1 and induces host cell cycle arrest at G2 to enable its proliferation. Cell Microbiol. 2008 Apr; 10(4):908-20.
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Apigenin inhibits pancreatic cancer cell proliferation through G2/M cell cycle arrest. Mol Cancer. 2006 Dec 29; 5:76.
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Benzyl isothiocyanate-induced DNA damage causes G2/M cell cycle arrest and apoptosis in human pancreatic cancer cells. J Nutr. 2006 Nov; 136(11):2728-34.
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Cell cycle-specified fluctuation of nucleosome occupancy at gene promoters. PLoS Genet. 2006 Sep 22; 2(9):e158.
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On the mechanisms of 12-O-tetradecanoylphorbol-13-acetate-induced growth arrest in pancreatic cancer cells. Pancreas. 2006 Aug; 33(2):148-55.
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Mechanistic insight into the allosteric activation of a ubiquitin-conjugating enzyme by RING-type ubiquitin ligases. Proc Natl Acad Sci U S A. 2005 Dec 27; 102(52):18890-5.
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Cell cycle regulation of central spindle assembly. Nature. 2004 Aug 19; 430(7002):908-13.