"Cyclin D" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cyclin subtype that is specific for CYCLIN-DEPENDENT KINASE 4 and CYCLIN-DEPENDENT KINASE 6. Unlike most cyclins, cyclin D expression is not cyclical, but rather it is expressed in response to proliferative signals. Cyclin D may therefore play a role in cellular responses to mitogenic signals.
| Descriptor ID |
D056741
|
| MeSH Number(s) |
D12.644.360.262.150 D12.776.167.218.150 D12.776.476.262.150
|
| Concept/Terms |
Cyclin D- Cyclin D
- Type D Cyclins
- Cyclins, Type D
- D Cyclins, Type
- Type D Cyclin
- Cyclin, Type D
- D Cyclin, Type
|
Below are MeSH descriptors whose meaning is more general than "Cyclin D".
Below are MeSH descriptors whose meaning is more specific than "Cyclin D".
This graph shows the total number of publications written about "Cyclin D" by people in this website by year, and whether "Cyclin D" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
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Below are the most recent publications written about "Cyclin D" by people in Profiles.
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Down-regulation of p57Kip2 induces prostate cancer in the mouse. Cancer Res. 2008 May 15; 68(10):3601-8.
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Epidermal growth factor receptor controls flat dysplastic aberrant crypt foci development and colon cancer progression in the rat azoxymethane model. Clin Cancer Res. 2008 Apr 15; 14(8):2253-62.
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Salmonella effector AvrA regulation of colonic epithelial cell inflammation by deubiquitination. Am J Pathol. 2007 Sep; 171(3):882-92.
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Loss of cyclin D1 impairs cerebellar development and suppresses medulloblastoma formation. Development. 2006 Oct; 133(19):3929-37.
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Repeated cocaine administration induces gene expression changes through the dopamine D1 receptors. Neuropsychopharmacology. 2005 Aug; 30(8):1443-54.
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Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E. Nature. 2002 May 16; 417(6886):299-304.
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The role of RBF in developmentally regulated cell proliferation in the eye disc and in Cyclin D/Cdk4 induced cellular growth. Development. 2002 Mar; 129(6):1345-56.
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Drosophila Cdk4 is required for normal growth and is dispensable for cell cycle progression. EMBO J. 2000 Sep 01; 19(17):4533-42.