Nuclear Receptor Coactivator 2
"Nuclear Receptor Coactivator 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcription factor that partners with ligand bound GLUCOCORTICOID RECEPTORS and ESTROGEN RECEPTORS to stimulate GENETIC TRANSCRIPTION. It plays an important role in FERTILITY as well as in METABOLISM of LIPIDS.
| Descriptor ID |
D051958
|
| MeSH Number(s) |
D12.644.360.024.314.200 D12.776.157.057.080.200 D12.776.476.024.394.200 D12.776.660.675.200 D12.776.930.617.200
|
| Concept/Terms |
Nuclear Receptor Coactivator 2- Nuclear Receptor Coactivator 2
- Steroid Receptor Coactivator SRC2
- Transcription Intermediary Factor 2
- Steroid Receptor Coactivator-2
- Steroid Receptor Coactivator 2
- Glucocorticoid Receptor-Interacting Protein 1
- Glucocorticoid Receptor Interacting Protein 1
|
Below are MeSH descriptors whose meaning is more general than "Nuclear Receptor Coactivator 2".
Below are MeSH descriptors whose meaning is more specific than "Nuclear Receptor Coactivator 2".
This graph shows the total number of publications written about "Nuclear Receptor Coactivator 2" by people in this website by year, and whether "Nuclear Receptor Coactivator 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 2 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "Nuclear Receptor Coactivator 2" by people in Profiles.
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GTF2A1-NCOA2-Associated Uterine Tumor Resembling Ovarian Sex Cord Tumor (UTROSCT) Shows Focal Rhabdoid Morphology and Aggressive Behavior. Am J Surg Pathol. 2021 12 01; 45(12):1725-1728.
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Recurrent MEIS1-NCOA2/1 fusions in a subset of low-grade spindle cell sarcomas frequently involving the genitourinary and gynecologic tracts. Mod Pathol. 2021 06; 34(6):1203-1212.
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Uterine Tumor Resembling Ovarian Sex Cord Stromal Tumor (UTROSCT): A Series of 3 Cases With Extensive Rhabdoid Differentiation, Malignant Behavior, and ESR1-NCOA2 Fusions. Am J Surg Pathol. 2020 11; 44(11):1563-1572.
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ETV3-NCOA2 in indeterminate cell histiocytosis: clonal translocation supports sui generis. Blood. 2015 Nov 12; 126(20):2344-5.
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PU.1-mediated upregulation of CSF1R is crucial for leukemia stem cell potential induced by MOZ-TIF2. Nat Med. 2010 May; 16(5):580-5, 1p following 585.
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Inhibition of androgen receptor transcriptional activity as a novel mechanism of action of arsenic. Mol Endocrinol. 2009 Mar; 23(3):412-21.
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Regulation of expression of thyroid hormone receptor isoforms and coactivators in liver and heart by thyroid hormone. Mol Cell Endocrinol. 2003 May 30; 203(1-2):65-75.
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Thyroid hormone receptor-specific interactions with steroid receptor coactivator-1 in the pituitary. Mol Endocrinol. 2003 May; 17(5):882-94.
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Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism. Nat Struct Biol. 2002 May; 9(5):359-64.
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Thyroid function in mice with compound heterozygous and homozygous disruptions of SRC-1 and TIF-2 coactivators: evidence for haploinsufficiency. Endocrinology. 2002 Apr; 143(4):1554-7.