Fas-Associated Death Domain Protein
"Fas-Associated Death Domain Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A signal-transducing adaptor protein that associates with TNF RECEPTOR complexes. It contains a death effector domain that can interact with death effector domains found on INITIATOR CASPASES such as CASPASE 8 and CASPASE 10. Activation of CASPASES via interaction with this protein plays a role in the signaling cascade that leads to APOPTOSIS.
| Descriptor ID |
D053200
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| MeSH Number(s) |
D12.644.360.024.285.200 D12.644.360.024.500.124 D12.644.360.075.421.200 D12.776.157.057.018.200 D12.776.157.057.500.124 D12.776.476.024.320.550 D12.776.476.024.500.124 D12.776.476.075.421.200
|
| Concept/Terms |
Fas-Associated Death Domain Protein- Fas-Associated Death Domain Protein
- Fas-Associating Protein with Death Domain
- Fas Associating Protein with Death Domain
- MORT1 Protein
- Fas Associated Death Domain Protein
- FADD Protein, Fas-Associating
- FADD Protein, Fas Associating
- Fas-Associating FADD Protein
- Fas-Associating Protein FADD
- FADD, Fas-Associating Protein
- Fas Associating Protein FADD
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Below are MeSH descriptors whose meaning is more general than "Fas-Associated Death Domain Protein".
Below are MeSH descriptors whose meaning is more specific than "Fas-Associated Death Domain Protein".
This graph shows the total number of publications written about "Fas-Associated Death Domain Protein" by people in this website by year, and whether "Fas-Associated Death Domain Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Fas-Associated Death Domain Protein" by people in Profiles.
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C5a induces caspase-dependent apoptosis in brain vascular endothelial cells in experimental lupus. Immunology. 2016 08; 148(4):407-19.
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Mechanism of Fas signaling regulation by human herpesvirus 8 K1 oncoprotein. J Natl Cancer Inst. 2009 Mar 18; 101(6):399-411.
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p38 MAPK and MSK1 mediate caspase-8 activation in manganese-induced mitochondria-dependent cell death. Cell Death Differ. 2007 Oct; 14(10):1826-36.
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Bleomycin induces alveolar epithelial cell death through JNK-dependent activation of the mitochondrial death pathway. Am J Physiol Lung Cell Mol Physiol. 2005 Oct; 289(4):L521-8.
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Phosphorylation of FADD at serine 194 by CKIalpha regulates its nonapoptotic activities. Mol Cell. 2005 Aug 05; 19(3):321-32.
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Fas ligation on macrophages enhances IL-1R1-Toll-like receptor 4 signaling and promotes chronic inflammation. Nat Immunol. 2004 Apr; 5(4):380-7.
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Hepatitis C virus NS5A protein impairs TNF-mediated hepatic apoptosis, but not by an anti-FAS antibody, in transgenic mice. Virology. 2002 Mar 01; 294(1):94-105.
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Molecular ordering of the initial signaling events of CD95. Mol Cell Biol. 2002 Jan; 22(1):207-20.
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The T cell death knell: immune-mediated tumor death in renal cell carcinoma. Clin Cancer Res. 2001 Oct; 7(10):3276-81.
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Rheumatoid arthritis synovial macrophages express the Fas-associated death domain-like interleukin-1beta-converting enzyme-inhibitory protein and are refractory to Fas-mediated apoptosis. Arthritis Rheum. 2001 Jan; 44(1):21-30.