TNF Receptor-Associated Factor 2
"TNF Receptor-Associated Factor 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A signal transducing tumor necrosis factor receptor associated factor that is involved in TNF RECEPTOR feedback regulation. It is similar in structure and appears to work in conjunction with TNF RECEPTOR-ASSOCIATED FACTOR 1 to inhibit APOPTOSIS.
| Descriptor ID |
D047992
|
| MeSH Number(s) |
D12.644.360.024.500.750 D12.776.157.057.500.750 D12.776.476.024.500.750
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "TNF Receptor-Associated Factor 2".
Below are MeSH descriptors whose meaning is more specific than "TNF Receptor-Associated Factor 2".
This graph shows the total number of publications written about "TNF Receptor-Associated Factor 2" by people in this website by year, and whether "TNF Receptor-Associated Factor 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "TNF Receptor-Associated Factor 2" by people in Profiles.
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The API2-MALT1 fusion exploits TNFR pathway-associated RIP1 ubiquitination to promote oncogenic NF-?B signaling. Oncogene. 2014 May 08; 33(19):2520-30.
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Site-specific ubiquitination is required for relieving the transcription factor Miz1-mediated suppression on TNF-a-induced JNK activation and inflammation. Proc Natl Acad Sci U S A. 2012 Jan 03; 109(1):191-6.
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Negative regulation of CD40-mediated B cell responses by E3 ubiquitin ligase Casitas-B-lineage lymphoma protein-B. J Immunol. 2007 Oct 01; 179(7):4473-9.
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Fractalkine (CX3CL1) stimulated by nuclear factor kappaB (NF-kappaB)-dependent inflammatory signals induces aortic smooth muscle cell proliferation through an autocrine pathway. Biochem J. 2003 Jul 15; 373(Pt 2):547-58.
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TCR-independent CD30 signaling selectively induces IL-13 production via a TNF receptor-associated factor/p38 mitogen-activated protein kinase-dependent mechanism. J Immunol. 2002 Sep 01; 169(5):2451-9.
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c-FLIP efficiently rescues TRAF-2-/- cells from TNF-induced apoptosis. Cell Death Differ. 2002 Feb; 9(2):138-44.
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Physical and functional interaction of filamin (actin-binding protein-280) and tumor necrosis factor receptor-associated factor 2. J Biol Chem. 2000 Jan 07; 275(1):271-8.