TNF Receptor-Associated Factor 4
"TNF Receptor-Associated Factor 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A widely expressed member of the TNF receptor-associated family that may play a role in neuronal development and EMBRYOGENESIS. Although TNF receptor-associated factor 4 does not strongly associate with TUMOR NECROSIS FACTOR RECEPTORS it may be a signaling partner with the GLUCOCORTICOID-INDUCED TNFR-RELATED PROTEIN that plays a role in the activation of JNK MITOGEN-ACTIVATED PROTEIN KINASES and NF-KAPPA B.
| Descriptor ID |
D053449
|
| MeSH Number(s) |
D12.644.360.024.500.906 D12.776.157.057.500.906 D12.776.476.024.500.906
|
| Concept/Terms |
TNF Receptor-Associated Factor 4- TNF Receptor-Associated Factor 4
- TNF Receptor Associated Factor 4
- TRAF4
- Cysteine-Rich Domain Associated with RING and TRAF Domains Protein 1
- Cysteine Rich Domain Associated with RING and TRAF Domains Protein 1
- TNF Receptor-Associated Protein 4
- TNF Receptor Associated Protein 4
|
Below are MeSH descriptors whose meaning is more general than "TNF Receptor-Associated Factor 4".
Below are MeSH descriptors whose meaning is more specific than "TNF Receptor-Associated Factor 4".
This graph shows the total number of publications written about "TNF Receptor-Associated Factor 4" by people in this website by year, and whether "TNF Receptor-Associated Factor 4" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
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Below are the most recent publications written about "TNF Receptor-Associated Factor 4" by people in Profiles.
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TRAF4 deficiency leads to tracheal malformation with resulting alterations in air flow to the lungs. Am J Pathol. 2000 Aug; 157(2):679-88.