Lymphotoxin alpha1, beta2 Heterotrimer
"Lymphotoxin alpha1, beta2 Heterotrimer" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heterotrimer complex consisting of one molecule of LYMPHOTOXIN-ALPHA and two molecules of the LYMPHOTOXIN-BETA. It is anchored to the cell surface via the transmembrane domains of the lymphotoxin-beta component and has specificity for the LYMPHOTOXIN BETA RECEPTOR. The lymphotoxin alpha1, beta2 heterotrimer plays a role in regulating lymphoid ORGANOGENESIS and the differentiation of certain subsets of NATURAL KILLER CELLS.
Descriptor ID |
D053361
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MeSH Number(s) |
D12.644.276.374.750.505 D12.776.467.374.750.505 D23.529.374.750.505
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Concept/Terms |
Lymphotoxin alpha1, beta2 Heterotrimer- Lymphotoxin alpha1, beta2 Heterotrimer
- Lymphotoxin alphabeta
- Lymphotoxin alphabeta Heterotrimer
- Heterotrimer, Lymphotoxin alphabeta
- alphabeta Heterotrimer, Lymphotoxin
- Lymphotoxin alpha1beta2
- alpha1beta2, Lymphotoxin
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Below are MeSH descriptors whose meaning is more general than "Lymphotoxin alpha1, beta2 Heterotrimer".
Below are MeSH descriptors whose meaning is more specific than "Lymphotoxin alpha1, beta2 Heterotrimer".
This graph shows the total number of publications written about "Lymphotoxin alpha1, beta2 Heterotrimer" by people in this website by year, and whether "Lymphotoxin alpha1, beta2 Heterotrimer" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2012 | 0 | 1 | 1 |
2014 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lymphotoxin alpha1, beta2 Heterotrimer" by people in Profiles.
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Type 3 innate lymphoid cell-derived lymphotoxin prevents microbiota-dependent inflammation. Cell Mol Immunol. 2018 07; 15(7):697-709.
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Innate lymphoid cells facilitate NK cell development through a lymphotoxin-mediated stromal microenvironment. J Exp Med. 2014 Jun 30; 211(7):1421-31.
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B cell maintenance of subcapsular sinus macrophages protects against a fatal viral infection independent of adaptive immunity. Immunity. 2012 Mar 23; 36(3):415-26.