"B-Cell Activating Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tumor necrosis factor superfamily member that plays a role in the regulation of B-LYMPHOCYTE survival. It occurs as a membrane-bound protein that is cleaved to release an biologically active soluble form with specificity to TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR PROTEIN; B-CELL ACTIVATION FACTOR RECEPTOR; and B-CELL MATURATION ANTIGEN.
| Descriptor ID |
D053264
|
| MeSH Number(s) |
D12.644.276.374.750.061 D12.776.395.191 D12.776.467.374.750.061 D12.776.543.550.193 D23.529.374.750.061
|
| Concept/Terms |
B-Cell Activating Factor- B-Cell Activating Factor
- Activating Factor, B-Cell
- B-Lymphocyte Activating Factor
- Activating Factor, B-Lymphocyte
- B Lymphocyte Activating Factor
- THANK Protein
- BAFF Ligand
- BLyS Protein
- B Cell Activating Factor
- B Lymphocyte Stimulator
- CD257 Antigen
- Antigen, CD257
- Antigens, CD257
- TNF and APOL-Related Leukocyte Expressed Ligand 1
- TNF and APOL Related Leukocyte Expressed Ligand 1
- TNF Superfamily, Member 13b
- Tumor Necrosis Factor Ligand Superfamily Member 13b
- CD257 Antigens
- TNFSF13B Protein
- TALL-1 Protein
- TALL 1 Protein
|
Below are MeSH descriptors whose meaning is more general than "B-Cell Activating Factor".
Below are MeSH descriptors whose meaning is more specific than "B-Cell Activating Factor".
This graph shows the total number of publications written about "B-Cell Activating Factor" by people in this website by year, and whether "B-Cell Activating Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 1 | 2 |
| 2017 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "B-Cell Activating Factor" by people in Profiles.
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BAFF promotes heightened BCR responsiveness and manifestations of chronic GVHD after allogeneic stem cell transplantation. Blood. 2021 05 06; 137(18):2544-2557.
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Unique Sjögren's syndrome patient subsets defined by molecular features. Rheumatology (Oxford). 2020 04 01; 59(4):860-868.
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Overexpression of the Cytokine BAFF and Autoimmunity Risk. N Engl J Med. 2017 04 27; 376(17):1615-1626.
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IgG-Immune Complexes Promote B Cell Memory by Inducing BAFF. J Immunol. 2016 Jan 01; 196(1):196-206.
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Targeting bone marrow lymphoid niches in acute lymphoblastic leukemia. Leuk Res. 2015 Dec; 39(12):1437-42.
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Metabolic reprogramming is required for antibody production that is suppressed in anergic but exaggerated in chronically BAFF-exposed B cells. J Immunol. 2014 Apr 15; 192(8):3626-36.
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Genetic variation in B cell-activating factor of the TNF family (BAFF) and asthma exacerbations among African American subjects. J Allergy Clin Immunol. 2012 Oct; 130(4):996-9.e6.
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B lymphocyte stimulator levels in systemic lupus erythematosus: higher circulating levels in African American patients and increased production after influenza vaccination in patients with low baseline levels. Arthritis Rheum. 2011 Dec; 63(12):3931-41.
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Biologic activity and safety of belimumab, a neutralizing anti-B-lymphocyte stimulator (BLyS) monoclonal antibody: a phase I trial in patients with systemic lupus erythematosus. Arthritis Res Ther. 2008; 10(5):R109.
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Characterization of a late transitional B cell population highly sensitive to BAFF-mediated homeostatic proliferation. J Exp Med. 2008 Jan 21; 205(1):155-68.