"Lymphotoxin-alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tumor necrosis factor family member that is released by activated LYMPHOCYTES. Soluble lymphotoxin is specific for TUMOR NECROSIS FACTOR RECEPTOR TYPE I; TUMOR NECROSIS FACTOR RECEPTOR TYPE II; and TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY, MEMBER 14. Lymphotoxin-alpha can form a membrane-bound heterodimer with LYMPHOTOXIN-BETA that has specificity for the LYMPHOTOXIN BETA RECEPTOR.
| Descriptor ID |
D008233
|
| MeSH Number(s) |
D12.644.276.374.480.438 D12.644.276.374.750.500 D12.776.467.374.480.438 D12.776.467.374.750.500 D23.529.374.480.438 D23.529.374.750.500
|
| Concept/Terms |
Lymphotoxin-alpha- Lymphotoxin-alpha
- Lymphotoxin alpha
- Lymphotoxin
- Tumor Necrosis Factor-beta
- Tumor Necrosis Factor beta
- TNF-beta
- Tumor Necrosis Factor Ligand Superfamily Member 1
- alpha-Lymphotoxin
- alpha Lymphotoxin
- TNF Superfamily, Member 1
Lymphotoxin-alpha3- Lymphotoxin-alpha3
- Lymphotoxin alpha3
- Soluble Lymphotoxin-alpha
- Lymphotoxin-alpha, Soluble
- Soluble Lymphotoxin alpha
|
Below are MeSH descriptors whose meaning is more general than "Lymphotoxin-alpha".
Below are MeSH descriptors whose meaning is more specific than "Lymphotoxin-alpha".
This graph shows the total number of publications written about "Lymphotoxin-alpha" by people in this website by year, and whether "Lymphotoxin-alpha" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 4 | 2 | 6 |
| 2003 | 4 | 2 | 6 |
| 2004 | 3 | 0 | 3 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2011 | 0 | 2 | 2 |
| 2012 | 2 | 0 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lymphotoxin-alpha" by people in Profiles.
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Circulating markers of inflammation and angiogenesis and clinical outcomes across subtypes of pulmonary arterial hypertension. J Heart Lung Transplant. 2023 02; 42(2):173-182.
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Pneumocystis-Driven Inducible Bronchus-Associated Lymphoid Tissue Formation Requires Th2 and Th17 Immunity. Cell Rep. 2017 03 28; 18(13):3078-3090.
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Cutting Edge: Lymphotoxin Signaling Is Essential for Clearance of Salmonella from the Gut Lumen and Generation of Anti-Salmonella Protective Immunity. J Immunol. 2017 01 01; 198(1):55-60.
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Innate lymphoid cells facilitate NK cell development through a lymphotoxin-mediated stromal microenvironment. J Exp Med. 2014 Jun 30; 211(7):1421-31.
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Lymphotoxin organizes contributions to host defense and metabolic illness from innate lymphoid cells. Cytokine Growth Factor Rev. 2014 Apr; 25(2):227-33.
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B cells produce CXCL13 in lymphoid neogenesis during chronic obstructive pulmonary disease. The new kid on the block? Am J Respir Crit Care Med. 2013 Jun 01; 187(11):1162-4.
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Linking the microbiota and metabolic disease with lymphotoxin. Int Immunol. 2013 Jul; 25(7):397-403.
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Lymphotoxin signalling in immune homeostasis and the control of microorganisms. Nat Rev Immunol. 2013 Apr; 13(4):270-9.
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Securing the border: lymphotoxin, IL-23 and IL-22 keep out the bad guys and 'fatten' the homeland. Nat Immunol. 2012 Oct; 13(10):940-1.
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Lymphotoxin regulates commensal responses to enable diet-induced obesity. Nat Immunol. 2012 Oct; 13(10):947-53.