"CD27 Ligand" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds to CD27 ANTIGEN. It is found on activated T-LYMPHOCYTES; B-LYMPHOCYTES; and DENDRITIC CELLS where it plays a role in stimulating the proliferation of CD4-POSITIVE T-LYMPHOCYTES and CD8-POSITIVE T-LYMPHOCYTES.
| Descriptor ID |
D053282
|
| MeSH Number(s) |
D12.644.276.374.750.030 D12.776.395.092 D12.776.467.374.750.030 D12.776.543.550.170 D23.529.374.750.030
|
| Concept/Terms |
CD27 Ligand- CD27 Ligand
- Ligand, CD27
- Antigens, CD70
- CD70 Antigens
- Tumor Necrosis Factor Ligand Superfamily Member 7
- CD27L Protein
- CD70 Antigen
- Antigen, CD70
- TNF Superfamily, Member 7
|
Below are MeSH descriptors whose meaning is more general than "CD27 Ligand".
Below are MeSH descriptors whose meaning is more specific than "CD27 Ligand".
This graph shows the total number of publications written about "CD27 Ligand" by people in this website by year, and whether "CD27 Ligand" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "CD27 Ligand" by people in Profiles.
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First-in-human multicenter phase I study of BMS-936561 (MDX-1203), an antibody-drug conjugate targeting CD70. Cancer Chemother Pharmacol. 2016 Jan; 77(1):155-62.