Antibody-Dependent Enhancement
"Antibody-Dependent Enhancement" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enhancement of viral infectivity caused by non-neutralizing antibodies. There are at least two mechanisms known to account for this: mediation by Fc receptors (RECEPTORS, FC) or by complement receptors (RECEPTORS, COMPLEMENT). Either the virus is complexed with antiviral IMMUNOGLOBULIN G and binds to Fc receptors, or virus is coated with antiviral IMMUNOGLOBULIN M and binds to complement receptors.
| Descriptor ID |
D019067
|
| MeSH Number(s) |
G06.920.095 G12.113
|
| Concept/Terms |
Antibody-Dependent Enhancement- Antibody-Dependent Enhancement
- Antibody Dependent Enhancement
- Antibody-Dependent Enhancements
- Enhancement, Antibody-Dependent
|
Below are MeSH descriptors whose meaning is more general than "Antibody-Dependent Enhancement".
Below are MeSH descriptors whose meaning is more specific than "Antibody-Dependent Enhancement".
This graph shows the total number of publications written about "Antibody-Dependent Enhancement" by people in this website by year, and whether "Antibody-Dependent Enhancement" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Antibody-Dependent Enhancement" by people in Profiles.
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Dengue envelope-based 'four-in-one' virus-like particles produced using Pichia pastoris induce enhancement-lacking, domain III-directed tetravalent neutralising antibodies in mice. Sci Rep. 2018 06 05; 8(1):8643.
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B Cell Responses during Secondary Dengue Virus Infection Are Dominated by Highly Cross-Reactive, Memory-Derived Plasmablasts. J Virol. 2016 06 15; 90(12):5574-85.
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A prospective nested case-control study of Dengue in infants: rethinking and refining the antibody-dependent enhancement dengue hemorrhagic fever model. PLoS Med. 2009 Oct; 6(10):e1000171.