Cyclin E
"Cyclin E" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 50-kDa protein that complexes with CYCLIN-DEPENDENT KINASE 2 in the late G1 phase of the cell cycle.
Descriptor ID |
D019927
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MeSH Number(s) |
D12.644.360.262.180 D12.776.167.218.180 D12.776.476.262.180
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cyclin E".
Below are MeSH descriptors whose meaning is more specific than "Cyclin E".
This graph shows the total number of publications written about "Cyclin E" by people in this website by year, and whether "Cyclin E" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1999 | 0 | 1 | 1 | 2000 | 0 | 1 | 1 | 2002 | 1 | 0 | 1 | 2003 | 1 | 0 | 1 | 2004 | 0 | 1 | 1 | 2006 | 0 | 2 | 2 | 2007 | 0 | 1 | 1 | 2008 | 1 | 2 | 3 | 2009 | 0 | 1 | 1 | 2010 | 5 | 1 | 6 | 2012 | 1 | 0 | 1 | 2013 | 1 | 0 | 1 | 2014 | 1 | 0 | 1 | 2015 | 0 | 1 | 1 | 2016 | 2 | 0 | 2 |
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Below are the most recent publications written about "Cyclin E" by people in Profiles.
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Stephenson MD, McQueen D, Winter M, Kliman HJ. Luteal start vaginal micronized progesterone improves pregnancy success in women with recurrent pregnancy loss. Fertil Steril. 2017 Mar; 107(3):684-690.e2.
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Hunt KK, Karakas C, Ha MJ, Biernacka A, Yi M, Sahin AA, Adjapong O, Hortobagyi GN, Bondy M, Thompson P, Cheung KL, Ellis IO, Bacus S, Symmans WF, Do KA, Keyomarsi K. Cytoplasmic Cyclin E Predicts Recurrence in Patients with Breast Cancer. Clin Cancer Res. 2017 Jun 15; 23(12):2991-3002.
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Karakas C, Biernacka A, Bui T, Sahin AA, Yi M, Akli S, Schafer J, Alexander A, Adjapong O, Hunt KK, Keyomarsi K. Cytoplasmic Cyclin E and Phospho-Cyclin-Dependent Kinase 2 Are Biomarkers of Aggressive Breast Cancer. Am J Pathol. 2016 07; 186(7):1900-1912.
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Patch AM, Christie EL, Etemadmoghadam D, Garsed DW, George J, Fereday S, Nones K, Cowin P, Alsop K, Bailey PJ, Kassahn KS, Newell F, Quinn MC, Kazakoff S, Quek K, Wilhelm-Benartzi C, Curry E, Leong HS. Whole-genome characterization of chemoresistant ovarian cancer. Nature. 2015 May 28; 521(7553):489-94.
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Siu KT, Xu Y, Swartz KL, Bhattacharyya M, Gurbuxani S, Hua Y, Minella AC. Chromosome instability underlies hematopoietic stem cell dysfunction and lymphoid neoplasia associated with impaired Fbw7-mediated cyclin E regulation. Mol Cell Biol. 2014 Sep; 34(17):3244-58.
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Wei Z, Hurtt R, Gu T, Bodzin AS, Koch WJ, Doria C. GRK2 negatively regulates IGF-1R signaling pathway and cyclins' expression in HepG2 cells. J Cell Physiol. 2013 Sep; 228(9):1897-901.
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Duong MT, Akli S, Macalou S, Biernacka A, Debeb BG, Yi M, Hunt KK, Keyomarsi K. Hbo1 is a cyclin E/CDK2 substrate that enriches breast cancer stem-like cells. Cancer Res. 2013 Sep 01; 73(17):5556-68.
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Siu KT, Rosner MR, Minella AC. An integrated view of cyclin E function and regulation. Cell Cycle. 2012 Jan 01; 11(1):57-64.
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Kapur P, Lotan Y, King E, Kabbani W, Mitra AP, Mosbah A, Abol-Enein H, Ghoneim M, Youssef RF. Primary adenocarcinoma of the urinary bladder: value of cell cycle biomarkers. Am J Clin Pathol. 2011 Jun; 135(6):822-30.
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Li F, Duman-Scheel M, Yang D, Du W, Zhang J, Zhao C, Qin L, Xin S. Sonic hedgehog signaling induces vascular smooth muscle cell proliferation via induction of the G1 cyclin-retinoblastoma axis. Arterioscler Thromb Vasc Biol. 2010 Sep; 30(9):1787-94.
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