 Receptors, Glycine
"Receptors, Glycine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface receptors that bind GLYCINE with high affinity and trigger intracellular changes which influence the behavior of cells. Glycine receptors in the CENTRAL NERVOUS SYSTEM have an intrinsic chloride channel and are usually inhibitory.
| Descriptor ID |
D018009
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| MeSH Number(s) |
D12.776.157.530.400.175.781 D12.776.157.530.400.400.100.200 D12.776.543.550.425.175.781 D12.776.543.550.425.500.100.200 D12.776.543.585.400.175.781 D12.776.543.585.400.500.100.200 D12.776.543.750.051.625 D12.776.543.750.720.200.470
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Receptors, Glycine".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Membrane Transport Proteins [D12.776.157.530]
- Ion Channels [D12.776.157.530.400]
- Chloride Channels [D12.776.157.530.400.175]
- Receptors, Glycine [D12.776.157.530.400.175.781]
- Ligand-Gated Ion Channels [D12.776.157.530.400.400]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.157.530.400.400.100]
- Receptors, Glycine [D12.776.157.530.400.400.100.200]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Ion Channels [D12.776.543.550.425]
- Chloride Channels [D12.776.543.550.425.175]
- Receptors, Glycine [D12.776.543.550.425.175.781]
- Ligand-Gated Ion Channels [D12.776.543.550.425.500]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.550.425.500.100]
- Receptors, Glycine [D12.776.543.550.425.500.100.200]
- Membrane Transport Proteins [D12.776.543.585]
- Ion Channels [D12.776.543.585.400]
- Chloride Channels [D12.776.543.585.400.175]
- Receptors, Glycine [D12.776.543.585.400.175.781]
- Ligand-Gated Ion Channels [D12.776.543.585.400.500]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.585.400.500.100]
- Receptors, Glycine [D12.776.543.585.400.500.100.200]
- Receptors, Cell Surface [D12.776.543.750]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.750.051]
- Receptors, Glycine [D12.776.543.750.051.625]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Amino Acid [D12.776.543.750.720.200]
- Receptors, Glycine [D12.776.543.750.720.200.470]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Glycine".
This graph shows the total number of publications written about "Receptors, Glycine" by people in this website by year, and whether "Receptors, Glycine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 2001 | 1 | 0 | 1 | | 2004 | 1 | 1 | 2 | | 2005 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 2 | 0 | 2 | | 2014 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, Glycine" by people in Profiles.
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Kumar A, Basak S, Rao S, Gicheru Y, Mayer ML, Sansom MSP, Chakrapani S. Mechanisms of activation and desensitization of full-length glycine receptor in lipid nanodiscs. Nat Commun. 2020 07 27; 11(1):3752.
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Förstera B, Muñoz B, Lobo MK, Chandra R, Lovinger DM, Aguayo LG. Presence of ethanol-sensitive glycine receptors in medium spiny neurons in the mouse nucleus accumbens. J Physiol. 2017 08 01; 595(15):5285-5300.
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Aguayo LG, Castro P, Mariqueo T, Muñoz B, Xiong W, Zhang L, Lovinger DM, Homanics GE. Altered sedative effects of ethanol in mice with a1 glycine receptor subunits that are insensitive to Gß? modulation. Neuropsychopharmacology. 2014 Oct; 39(11):2538-48.
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Borghese CM, Xiong W, Oh SI, Ho A, Mihic SJ, Zhang L, Lovinger DM, Homanics GE, Eger EI, Harris RA. Mutations M287L and Q266I in the glycine receptor a1 subunit change sensitivity to volatile anesthetics in oocytes and neurons, but not the minimal alveolar concentration in knockin mice. Anesthesiology. 2012 Oct; 117(4):765-71.
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Xiong W, Wu X, Li F, Cheng K, Rice KC, Lovinger DM, Zhang L. A common molecular basis for exogenous and endogenous cannabinoid potentiation of glycine receptors. J Neurosci. 2012 Apr 11; 32(15):5200-8.
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Borghese CM, Blednov YA, Quan Y, Iyer SV, Xiong W, Mihic SJ, Zhang L, Lovinger DM, Trudell JR, Homanics GE, Harris RA. Characterization of two mutations, M287L and Q266I, in the a1 glycine receptor subunit that modify sensitivity to alcohols. J Pharmacol Exp Ther. 2012 Feb; 340(2):304-16.
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Traka M, Seburn KL, Popko B. Nmf11 is a novel ENU-induced mutation in the mouse glycine receptor alpha 1 subunit. Mamm Genome. 2006 Sep; 17(9):950-5.
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Genzen JR, McGehee DS. Nicotinic modulation of GABAergic synaptic transmission in the spinal cord dorsal horn. Brain Res. 2005 Jan 21; 1031(2):229-37.
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Hall AC, Turcotte CM, Betts BA, Yeung WY, Agyeman AS, Burk LA. Modulation of human GABAA and glycine receptor currents by menthol and related monoterpenoids. Eur J Pharmacol. 2004 Dec 03; 506(1):9-16.
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Peña F, Parkis MA, Tryba AK, Ramirez JM. Differential contribution of pacemaker properties to the generation of respiratory rhythms during normoxia and hypoxia. Neuron. 2004 Jul 08; 43(1):105-17.
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