The University of Chicago Header Logo

Cassandra Hayne

TitleAssistant Professor
InstitutionUniversity of Chicago
DepartmentBiochemistry and Molecular Biology
AddressChicago IL 60637
Email
vCardDownload vCard

    Collapse Overview 

    Collapse Biography 
    Collapse education and training
    National Institute of Environmental Health Sciences, RTP, NCPostdoctoral Fellowship2022Biochemistry & Structural Biology
    University of North Carolina at Chapel Hill, Chapel Hill, NCPh.D.2017Biochemistry
    University of Northern Iowa, Cedar Falls, IAB.A./B.S.2011Biochemistry & Biology
    Collapse awards and honors
    2013Graduate Research Fellowship, NSF
    2021MOSAIC K99/R00, NIGMS/NIH

    Collapse Featured Content 
    Collapse Twitter

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Hayne CK, Butay KJU, Stewart ZD, Krahn JM, Perera L, Williams JG, Petrovitch RM, Deterding LJ, Matera AG, Borgnia MJ, Stanley RE. Author Correction: Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex. Nat Struct Mol Biol. 2024 Feb; 31(2):390. PMID: 38196035.
      Citations:    Fields:    
    2. Hayne CK, Sekulovski S, Hurtig JE, Stanley RE, Trowitzsch S, van Hoof A. New insights into RNA processing by the eukaryotic tRNA splicing endonuclease. J Biol Chem. 2023 09; 299(9):105138. PMID: 37544645; PMCID: PMC10485636.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    3. Hayne CK, Butay KJU, Stewart ZD, Krahn JM, Perera L, Williams JG, Petrovitch RM, Deterding LJ, Matera AG, Borgnia MJ, Stanley RE. Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex. Nat Struct Mol Biol. 2023 06; 30(6):824-833. PMID: 37231153; PMCID: PMC10627149.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    4. Hayne CK, Lewis TA, Stanley RE. Recent insights into the structure, function, and regulation of the eukaryotic transfer RNA splicing endonuclease complex. Wiley Interdiscip Rev RNA. 2022 09; 13(5):e1717. PMID: 35156311; PMCID: PMC9465713.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    5. Pillon MC, Frazier MN, Dillard LB, Williams JG, Kocaman S, Krahn JM, Perera L, Hayne CK, Gordon J, Stewart ZD, Sobhany M, Deterding LJ, Hsu AL, Dandey VP, Borgnia MJ, Stanley RE. Cryo-EM structures of the SARS-CoV-2 endoribonuclease Nsp15 reveal insight into nuclease specificity and dynamics. Nat Commun. 2021 01 27; 12(1):636. PMID: 33504779; PMCID: PMC7840905.
      Citations: 46     Fields:    Translation:Cells
    6. Hayne CK, Schmidt CA, Haque MI, Matera AG, Stanley RE. Reconstitution of the human tRNA splicing endonuclease complex: insight into the regulation of pre-tRNA cleavage. Nucleic Acids Res. 2020 08 20; 48(14):7609-7622. PMID: 32476018; PMCID: PMC7641302.
      Citations: 20     Fields:    Translation:HumansCells
    7. Hayne CK, Yumerefendi H, Cao L, Gauer JW, Lafferty MJ, Kuhlman B, Erie DA, Neher SB. We FRET so You Don't Have To: New Models of the Lipoprotein Lipase Dimer. Biochemistry. 2018 01 16; 57(2):241-254. PMID: 29303250; PMCID: PMC5860654.
      Citations: 8     Fields:    Translation:HumansCells
    8. Hayne CK, Lafferty MJ, Eglinger BJ, Kane JP, Neher SB. Biochemical Analysis of the Lipoprotein Lipase Truncation Variant, LPLS447X, Reveals Increased Lipoprotein Uptake. Biochemistry. 2017 01 24; 56(3):525-533. PMID: 27984852; PMCID: PMC5848218.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    9. Garrett CK, Broadwell LJ, Hayne CK, Neher SB. Modulation of the Activity of Mycobacterium tuberculosis LipY by Its PE Domain. PLoS One. 2015; 10(8):e0135447. PMID: 26270534; PMCID: PMC4536007.
      Citations: 10     Fields:    Translation:Cells
    Hayne's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (62)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _
    Physical Neighbors
    _