 Sodium-Potassium-Chloride Symporters
"Sodium-Potassium-Chloride Symporters" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of symporters that specifically transport SODIUM CHLORIDE and POTASSIUM CHLORIDE across cellular membranes in a tightly coupled process.
| Descriptor ID |
D028021
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| MeSH Number(s) |
D12.776.157.530.450.625.750 D12.776.543.585.450.625.750
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| Concept/Terms |
Sodium-Potassium-Chloride Symporters- Sodium-Potassium-Chloride Symporters
- Sodium Potassium Chloride Symporters
- Symporters, Sodium-Potassium-Chloride
- Na-K-Cl-Symporter
- Na K Cl Symporter
- Na-K-Cl-Transporter
- Na K Cl Transporter
- Sodium-Potassium-Chloride Cotransporters
- Cotransporters, Sodium-Potassium-Chloride
- Sodium Potassium Chloride Cotransporters
- NaK2Cl Symporter
- Symporter, NaK2Cl
- Sodium, Potassium, Chloride-Cotransporter
- Sodium-Potassium-Chloride Cotransporter
- Cotransporter, Sodium-Potassium-Chloride
- Sodium Potassium Chloride Cotransporter
- Na(+), K(+), Cl(-)-Cotransporter
- NaCl-KCl Cotransporter
- Cotransporter, NaCl-KCl
- NaCl KCl Cotransporter
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Below are MeSH descriptors whose meaning is more general than "Sodium-Potassium-Chloride Symporters".
Below are MeSH descriptors whose meaning is more specific than "Sodium-Potassium-Chloride Symporters".
This graph shows the total number of publications written about "Sodium-Potassium-Chloride Symporters" by people in this website by year, and whether "Sodium-Potassium-Chloride Symporters" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 2 | 2 | | 2002 | 1 | 1 | 2 | | 2003 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2009 | 1 | 1 | 2 | | 2010 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sodium-Potassium-Chloride Symporters" by people in Profiles.
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Orlov SN, Koltsova SV, Kapilevich LV, Dulin NO, Gusakova SV. Cation-chloride cotransporters: regulation, physiological significance, and role in pathogenesis of arterial hypertension. Biochemistry (Mosc). 2014 Dec; 79(13):1546-61.
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Bouyer PG, Tang X, Weber CR, Shen L, Turner JR, Matthews JB. Capsaicin induces NKCC1 internalization and inhibits chloride secretion in colonic epithelial cells independently of TRPV1. Am J Physiol Gastrointest Liver Physiol. 2013 Jan 15; 304(2):G142-56.
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Tang J, Bouyer P, Mykoniatis A, Buschmann M, Matlin KS, Matthews JB. Activated PKC{delta} and PKC{epsilon} inhibit epithelial chloride secretion response to cAMP via inducing internalization of the Na+-K+-2Cl- cotransporter NKCC1. J Biol Chem. 2010 Oct 29; 285(44):34072-85.
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Mykoniatis A, Shen L, Fedor-Chaiken M, Tang J, Tang X, Worrell RT, Delpire E, Turner JR, Matlin KS, Bouyer P, Matthews JB. Phorbol 12-myristate 13-acetate-induced endocytosis of the Na-K-2Cl cotransporter in MDCK cells is associated with a clathrin-dependent pathway. Am J Physiol Cell Physiol. 2010 Jan; 298(1):C85-97.
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Kim SH, Kim KX, Raveendran NN, Wu T, Pondugula SR, Marcus DC. Regulation of ENaC-mediated sodium transport by glucocorticoids in Reissner's membrane epithelium. Am J Physiol Cell Physiol. 2009 Mar; 296(3):C544-57.
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Worrell RT, Merk L, Matthews JB. Ammonium transport in the colonic crypt cell line, T84: role for Rhesus glycoproteins and NKCC1. Am J Physiol Gastrointest Liver Physiol. 2008 Feb; 294(2):G429-40.
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Del Castillo IC, Fedor-Chaiken M, Song JC, Starlinger V, Yoo J, Matlin KS, Matthews JB. Dynamic regulation of Na(+)-K(+)-2Cl(-) cotransporter surface expression by PKC-{epsilon} in Cl(-)--secretory epithelia. Am J Physiol Cell Physiol. 2005 Nov; 289(5):C1332-42.
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Anfinogenova YJ, Baskakov MB, Kovalev IV, Kilin AA, Dulin NO, Orlov SN. Cell-volume-dependent vascular smooth muscle contraction: role of Na+, K+, 2Cl- cotransport, intracellular Cl- and L-type Ca2+ channels. Pflugers Arch. 2004 Oct; 449(1):42-55.
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Kahle KT, Gimenez I, Hassan H, Wilson FH, Wong RD, Forbush B, Aronson PS, Lifton RP. WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia. Proc Natl Acad Sci U S A. 2004 Feb 17; 101(7):2064-9.
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Worrell RT, Oghene J, Matthews JB. Ammonium effects on colonic Cl- secretion: anomalous mole fraction behavior. Am J Physiol Gastrointest Liver Physiol. 2004 Jan; 286(1):G14-22.
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