Cyclin A
"Cyclin A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cyclin subtype that has specificity for CDC2 PROTEIN KINASE and CYCLIN-DEPENDENT KINASE 2. It plays a role in progression of the CELL CYCLE through G1/S and G2/M phase transitions.
Descriptor ID |
D019925
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MeSH Number(s) |
D12.644.360.262.100 D12.776.167.218.100 D12.776.476.262.100
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Concept/Terms |
Cyclin A- Cyclin A
- E1A p60
- Type A Cyclins
- Cyclins, Type A
- Adenovirus E1A-Associated Protein p60
- Adenovirus E1A Associated Protein p60
- Type A Cyclin
- Cyclin, Type A
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Below are MeSH descriptors whose meaning is more general than "Cyclin A".
Below are MeSH descriptors whose meaning is more specific than "Cyclin A".
This graph shows the total number of publications written about "Cyclin A" by people in this website by year, and whether "Cyclin A" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1997 | 0 | 1 | 1 | 2000 | 1 | 0 | 1 | 2004 | 0 | 1 | 1 | 2006 | 0 | 3 | 3 | 2007 | 0 | 3 | 3 | 2008 | 0 | 2 | 2 | 2009 | 0 | 2 | 2 | 2010 | 0 | 1 | 1 | 2011 | 0 | 1 | 1 | 2013 | 0 | 1 | 1 | 2014 | 0 | 1 | 1 | 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclin A" by people in Profiles.
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Wang CZ, Luo Y, Huang WH, Zeng J, Zhang CF, Lager M, Du W, Xu M, Yuan CS. Falcarindiol and dichloromethane fraction are bioactive components in Oplopanax elatus: Colorectal cancer chemoprevention via induction of apoptosis and G2/M cell cycle arrest mediated by cyclin A upregulation. J Appl Biomed. 2021; 19(2):113-124.
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Huskey NE, Guo T, Evason KJ, Momcilovic O, Pardo D, Creasman KJ, Judson RL, Blelloch R, Oakes SA, Hebrok M, Goga A. CDK1 inhibition targets the p53-NOXA-MCL1 axis, selectively kills embryonic stem cells, and prevents teratoma formation. Stem Cell Reports. 2015 Mar 10; 4(3):374-89.
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Ji YB, Ling N, Zhou XJ, Mao YX, Li WL, Chen N. Schedule-dependent effects of kappa-selenocarrageenan in combination with epirubicin on hepatocellular carcinoma. Asian Pac J Cancer Prev. 2014; 15(8):3651-7.
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Wei Z, Hurtt R, Gu T, Bodzin AS, Koch WJ, Doria C. GRK2 negatively regulates IGF-1R signaling pathway and cyclins' expression in HepG2 cells. J Cell Physiol. 2013 Sep; 228(9):1897-901.
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Wang CZ, Calway TD, Wen XD, Smith J, Yu C, Wang Y, Mehendale SR, Yuan CS. Hydrophobic flavonoids from Scutellaria baicalensis induce colorectal cancer cell apoptosis through a mitochondrial-mediated pathway. Int J Oncol. 2013 Mar; 42(3):1018-26.
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Gundacker C, Scheinast M, Damjanovic L, Fuchs C, Rosner M, Hengstschläger M. Proliferation potential of human amniotic fluid stem cells differently responds to mercury and lead exposure. Amino Acids. 2012 Aug; 43(2):937-49.
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Heiferman MJ, Salabat MR, Ujiki MB, Strouch MJ, Cheon EC, Silverman RB, Bentrem DJ. Sansalvamide induces pancreatic cancer growth arrest through changes in the cell cycle. Anticancer Res. 2010 Jan; 30(1):73-8.
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Wang CZ, Aung HH, Mehendale SR, Shoyama Y, Yuan CS. High performance liquid chromatographic analysis and anticancer potential of Oplopanax horridus: comparison of stem and berry extracts. Fitoterapia. 2010 Mar; 81(2):132-9.
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Wang CZ, Li XL, Sun S, Xie JT, Aung HH, Tong R, McEntee E, Yuan CS. Methylnaltrexone, a peripherally acting opioid receptor antagonist, enhances tumoricidal effects of 5-Fu on human carcinoma cells. Anticancer Res. 2009 Aug; 29(8):2927-32.
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Shen H, Moran DM, Maki CG. Transient nutlin-3a treatment promotes endoreduplication and the generation of therapy-resistant tetraploid cells. Cancer Res. 2008 Oct 15; 68(20):8260-8.
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