"Claudins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large family of transmembrane proteins found in TIGHT JUNCTIONS. They take part in the formation of paracellular barriers and pores that regulate paracellular permeability.
| Descriptor ID |
D057167
|
| MeSH Number(s) |
D12.776.543.940.200
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Claudins".
Below are MeSH descriptors whose meaning is more specific than "Claudins".
This graph shows the total number of publications written about "Claudins" by people in this website by year, and whether "Claudins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 2 | 0 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 3 | 0 | 3 |
| 2020 | 1 | 1 | 2 |
| 2021 | 0 | 1 | 1 |
| 2022 | 3 | 2 | 5 |
| 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "Claudins" by people in Profiles.
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Expression of therapy target molecules in esophagogastric junction and Barrett's adenocarcinoma. Gastric Cancer. 2025 Mar; 28(2):264-274.
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Computational Models of Claudin Assembly in Tight Junctions and Strand Properties. Int J Mol Sci. 2024 Mar 16; 25(6).
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Molecular mechanism of claudin-15 strand flexibility: A computational study. J Gen Physiol. 2022 12 05; 154(12).
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Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes. J Biol Chem. 2022 09; 298(9):102357.
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Computational study of ion permeation through claudin-4 paracellular channels. Ann N Y Acad Sci. 2022 10; 1516(1):162-174.
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Tight junction proteins occludin and ZO-1 as regulators of epithelial proliferation and survival. Ann N Y Acad Sci. 2022 08; 1514(1):21-33.
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Identification of Claudin 6-specific HLA class I- and HLA class II-restricted T cell receptors for cellular immunotherapy in ovarian cancer. Oncoimmunology. 2022; 11(1):2020983.
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T cell protein tyrosine phosphatase protects intestinal barrier function by restricting epithelial tight junction remodeling. J Clin Invest. 2021 09 01; 131(17).
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Idiopathic pulmonary fibrosis is associated with tight junction protein alterations. Biochim Biophys Acta Biomembr. 2020 05 01; 1862(5):183205.
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Computational Modeling of Claudin Structure and Function. Int J Mol Sci. 2020 Jan 23; 21(3).