"Claudin-4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A claudin subtype that takes part in maintaining the barrier-forming property of TIGHT JUNCTIONS. Claudin-4 is found associated with CLAUDIN-8 in the KIDNEY COLLECTING DUCT where it may play a role in paracellular chloride ion reabsorption.
| Descriptor ID |
D062506
|
| MeSH Number(s) |
D12.776.543.940.200.400
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Claudin-4".
Below are MeSH descriptors whose meaning is more specific than "Claudin-4".
This graph shows the total number of publications written about "Claudin-4" by people in this website by year, and whether "Claudin-4" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2022 | 0 | 2 | 2 |
| 2024 | 2 | 0 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Claudin-4" by people in Profiles.
-
Cryo-EM structures of Clostridium perfringens enterotoxin bound to its human receptor, claudin-4. Structure. 2024 Nov 07; 32(11):1936-1951.e5.
-
Structural and biophysical insights into targeting of claudin-4 by a synthetic antibody fragment. Commun Biol. 2024 Jun 17; 7(1):733.
-
Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes. J Biol Chem. 2022 09; 298(9):102357.
-
Computational study of ion permeation through claudin-4 paracellular channels. Ann N Y Acad Sci. 2022 10; 1516(1):162-174.
-
Idiopathic pulmonary fibrosis is associated with tight junction protein alterations. Biochim Biophys Acta Biomembr. 2020 05 01; 1862(5):183205.
-
Occludin S408 phosphorylation regulates tight junction protein interactions and barrier function. J Cell Biol. 2011 May 02; 193(3):565-82.