CASP8 and FADD-Like Apoptosis Regulating Protein
"CASP8 and FADD-Like Apoptosis Regulating Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An APOPTOSIS-regulating protein that is structurally related to CASPASE 8 and competes with CASPASE 8 for binding to FAS ASSOCIATED DEATH DOMAIN PROTEIN. Two forms of CASP8 and FADD-like apoptosis regulating protein exist, a long form containing a caspase-like enzymatically inactive domain and a short form which lacks the caspase-like domain.
| Descriptor ID |
D053446
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| MeSH Number(s) |
D12.644.360.024.285.024 D12.644.360.024.500.024 D12.644.360.075.421.024 D12.776.157.057.018.024 D12.776.476.075.421.024
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "CASP8 and FADD-Like Apoptosis Regulating Protein".
Below are MeSH descriptors whose meaning is more specific than "CASP8 and FADD-Like Apoptosis Regulating Protein".
This graph shows the total number of publications written about "CASP8 and FADD-Like Apoptosis Regulating Protein" by people in this website by year, and whether "CASP8 and FADD-Like Apoptosis Regulating Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2001 | 0 | 3 | 3 |
| 2002 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 2 | 2 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "CASP8 and FADD-Like Apoptosis Regulating Protein" by people in Profiles.
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Omacetaxine added to a standard acute myeloid leukaemia chemotherapy regimen reduces cellular FLIP levels, markedly increasing the incidence of eccrine hidradenitis. Br J Haematol. 2021 11; 195(3):e138-e141.
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FLIP: a novel regulator of macrophage differentiation and granulocyte homeostasis. Blood. 2010 Dec 02; 116(23):4968-77.
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Altered thymic selection by overexpressing cellular FLICE inhibitory protein in T cells causes lupus-like syndrome in a BALB/c but not C57BL/6 strain. Cell Death Differ. 2010 Mar; 17(3):522-33.
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The late phase of ischemic preconditioning induces a prosurvival genetic program that results in marked attenuation of apoptosis. J Mol Cell Cardiol. 2007 Jun; 42(6):1075-85.
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The Fas pathway is involved in pancreatic beta cell secretory function. Proc Natl Acad Sci U S A. 2007 Feb 20; 104(8):2861-6.
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A five-year itch in TNF-alpha cytotoxicity: the time factor determines JNK action. Dev Cell. 2006 Mar; 10(3):277-8.
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NF-kappaB-regulated expression of cellular FLIP protects rheumatoid arthritis synovial fibroblasts from tumor necrosis factor alpha-mediated apoptosis. Arthritis Rheum. 2004 Dec; 50(12):3844-55.
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Stat1-dependent induction of tumor necrosis factor-related apoptosis-inducing ligand and the cell-surface death signaling pathway by interferon beta in human cancer cells. Cancer Res. 2003 Sep 01; 63(17):5299-307.
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Differential recruitment of caspase 8 to cFlip confers sensitivity or resistance to Fas-mediated apoptosis in a subset of familial lymphoma patients. Leuk Res. 2003 Sep; 27(9):841-51.
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TNF-related apoptosis-inducing ligand (TRAIL) frequently induces apoptosis in Philadelphia chromosome-positive leukemia cells. Blood. 2003 May 01; 101(9):3658-67.