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PAI-1-regulated extracellular proteolysis governs senescence and survival in Klotho mice.
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PAI-1-regulated extracellular proteolysis governs senescence and survival in Klotho mice.
PAI-1-regulated extracellular proteolysis governs senescence and survival in Klotho mice. Proc Natl Acad Sci U S A. 2014 May 13; 111(19):7090-5.
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PubMed
subject areas
Aging
Animals
Cellular Senescence
Cyclin-Dependent Kinase Inhibitor p16
Extracellular Space
Female
Glucuronidase
Hemorrhagic Disorders
Longevity
Male
Mice
Mice, Inbred C3H
Mice, Inbred C57BL
Mice, Knockout
Phenotype
Plasminogen Activator Inhibitor 1
Proteolysis
Serpin E2
Telomere
authors with profiles
Gokhan M. Mutlu