 Colchicine
"Colchicine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A major alkaloid from Colchicum autumnale L. and found also in other Colchicum species. Its primary therapeutic use is in the treatment of gout, but it has been used also in the therapy of familial Mediterranean fever (PERIODIC DISEASE).
| Descriptor ID |
D003078
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| MeSH Number(s) |
D03.132.225
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Colchicine".
Below are MeSH descriptors whose meaning is more specific than "Colchicine".
This graph shows the total number of publications written about "Colchicine" by people in this website by year, and whether "Colchicine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 1 | 1 | | 1987 | 0 | 1 | 1 | | 1989 | 0 | 1 | 1 | | 1993 | 1 | 0 | 1 | | 1994 | 0 | 1 | 1 | | 1996 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2013 | 0 | 3 | 3 | | 2014 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Colchicine" by people in Profiles.
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Saag KG, Becker MA, Whelton A, Hunt B, Castillo M, Kisfalvi K, Gunawardhana L. Efficacy and Safety of Febuxostat Extended and Immediate Release in Patients With Gout and Renal Impairment: A Phase III Placebo-Controlled Study. Arthritis Rheumatol. 2019 01; 71(1):143-153.
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Prins KW, Tian L, Wu D, Thenappan T, Metzger JM, Archer SL. Colchicine Depolymerizes Microtubules, Increases Junctophilin-2, and Improves Right Ventricular Function in Experimental Pulmonary Arterial Hypertension. J Am Heart Assoc. 2017 May 31; 6(6).
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Becker MA, Fitz-Patrick D, Choi HK, Dalbeth N, Storgard C, Cravets M, Baumgartner S. An open-label, 6-month study of allopurinol safety in gout: The LASSO study. Semin Arthritis Rheum. 2015 Oct; 45(2):174-83.
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Paul S, Sepehr GJ, Weinstein B, Roper J. Co-occurrence of idiopathic granulomatous hepatitis and primary biliary cirrhosis. Dig Dis Sci. 2014 Nov; 59(11):2831-5.
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Donoghue MT, Fort A, Clifton R, Zhang X, McKeown PC, Voigt-Zielinksi ML, Borevitz JO, Spillane C. C(m)CGG methylation-independent parent-of-origin effects on genome-wide transcript levels in isogenic reciprocal F1 triploid plants. DNA Res. 2014; 21(2):141-51.
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Sandbo N, Ngam C, Torr E, Kregel S, Kach J, Dulin N. Control of myofibroblast differentiation by microtubule dynamics through a regulated localization of mDia2. J Biol Chem. 2013 May 31; 288(22):15466-73.
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Mutyal NN, Radosevich A, Tiwari AK, Stypula Y, Wali R, Kunte D, Roy HK, Backman V. Biological mechanisms underlying structural changes induced by colorectal field carcinogenesis measured with low-coherence enhanced backscattering (LEBS) spectroscopy. PLoS One. 2013; 8(2):e57206.
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Larsen SM, Levine LA. Peyronie's disease: review of nonsurgical treatment options. Urol Clin North Am. 2011 May; 38(2):195-205.
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Damania D, Subramanian H, Tiwari AK, Stypula Y, Kunte D, Pradhan P, Roy HK, Backman V. Role of cytoskeleton in controlling the disorder strength of cellular nanoscale architecture. Biophys J. 2010 Aug 04; 99(3):989-96.
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Wong VK, Chiu P, Chung SS, Chow LM, Zhao YZ, Yang BB, Ko BC. Pseudolaric acid B, a novel microtubule-destabilizing agent that circumvents multidrug resistance phenotype and exhibits antitumor activity in vivo. Clin Cancer Res. 2005 Aug 15; 11(16):6002-11.
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