Discoidin Domain Receptors
"Discoidin Domain Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Receptor tyrosine kinases that bind COLLAGENS. They are characterized by the presence of extracellular DISCOIDIN DOMAINS that activate SIGNAL TRANSDUCTION PATHWAYS in response to collagen binding. They may also be cleaved by MATRIX METALLOPROTEINASES to mediate cell interactions with the EXTRACELLULAR MATRIX.
| Descriptor ID |
D000070818
|
| MeSH Number(s) |
D08.811.913.696.620.682.725.400.005 D12.776.543.750.630.005 D12.776.543.750.685.050 D12.776.543.750.705.880.300
|
| Concept/Terms |
Discoidin Domain Receptors- Discoidin Domain Receptors
- Receptors, Discoidin Domain
- DDR Proteins
- Proteins, DDR
- Discoidin Domain Receptor
- Receptor, Discoidin Domain
|
Below are MeSH descriptors whose meaning is more general than "Discoidin Domain Receptors".
Below are MeSH descriptors whose meaning is more specific than "Discoidin Domain Receptors".
This graph shows the total number of publications written about "Discoidin Domain Receptors" by people in this website by year, and whether "Discoidin Domain Receptors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
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Below are the most recent publications written about "Discoidin Domain Receptors" by people in Profiles.
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Discoidin domain receptor 1 receptor tyrosine kinase induces cyclooxygenase-2 and promotes chemoresistance through nuclear factor-kappaB pathway activation. Cancer Res. 2006 Aug 15; 66(16):8123-30.