"ADAM10 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A disintegrin and metalloproteinase domain-containing protein. It cleaves the membrane-bound precursor of TUMOR NECROSIS FACTOR-ALPHA between ALANINE 76 and VALINE 77 to its functional form, as well as several other CELL SURFACE PROTEINS to their soluble forms, including AMYLOID BETA-PROTEIN PRECURSOR and PRION PROTEIN.
| Descriptor ID |
D000072197
|
| MeSH Number(s) |
D08.811.277.656.675.374.102.250 D09.400.430.500.250 D12.776.395.033.250
|
| Concept/Terms |
ADAM10 Protein- ADAM10 Protein
- CD156w Antigen
- Antigen, CD156w
- CD156c Antigen
- Antigen, CD156c
- Disintegrin and Metalloproteinase Domain-Containing Protein 10
- Disintegrin and Metalloproteinase Domain Containing Protein 10
- ADAM-10 Protein
- ADAM 10 Protein
|
Below are MeSH descriptors whose meaning is more general than "ADAM10 Protein".
Below are MeSH descriptors whose meaning is more specific than "ADAM10 Protein".
This graph shows the total number of publications written about "ADAM10 Protein" by people in this website by year, and whether "ADAM10 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "ADAM10 Protein" by people in Profiles.
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Sphingosine-1-Phosphate Receptor 3 Induces Endothelial Barrier Loss via ADAM10-Mediated Vascular Endothelial-Cadherin Cleavage. Int J Mol Sci. 2023 Nov 08; 24(22).
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Spatial competition shapes the dynamic mutational landscape of normal esophageal epithelium. Nat Genet. 2020 06; 52(6):604-614.
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Staphylococcus aureus alpha toxin activates Notch in vascular cells. Angiogenesis. 2019 02; 22(1):197-209.
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Auto-Assembling Detoxified Staphylococcus aureus Alpha-Hemolysin Mimicking the Wild-Type Cytolytic Toxin. Clin Vaccine Immunol. 2016 06; 23(6):442-50.
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Synergistic Action of Staphylococcus aureus a-Toxin on Platelets and Myeloid Lineage Cells Contributes to Lethal Sepsis. Cell Host Microbe. 2015 Jun 10; 17(6):775-87.
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Epithelial innate immune response to Acinetobacter baumannii challenge. Infect Immun. 2014 Nov; 82(11):4458-65.
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Spatial organization of EphA2 at the cell-cell interface modulates trans-endocytosis of ephrinA1. Biophys J. 2014 May 20; 106(10):2196-205.
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Tissue-specific patterning of host innate immune responses by Staphylococcus aureus a-toxin. J Innate Immun. 2014; 6(5):619-31.
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ADAM10 mediates vascular injury induced by Staphylococcus aureus a-hemolysin. J Infect Dis. 2012 Aug 01; 206(3):352-6.
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Genetic requirement for ADAM10 in severe Staphylococcus aureus skin infection. J Invest Dermatol. 2012 May; 132(5):1513-6.