Apc11 Subunit, Anaphase-Promoting Complex-Cyclosome
"Apc11 Subunit, Anaphase-Promoting Complex-Cyclosome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Together with the Apc2 subunit, forms the catalytic core of the E3 ubiquitin ligase, anaphase-promoting complex-cyclosome. It has a RING H2 domain which interacts with the cullin domain of Apc2. Apc11 also interacts with the E2 ubiquitin ligases involved in APC-C ubiquitination reactions.
Descriptor ID |
D064198
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MeSH Number(s) |
D08.811.464.938.750.092.687 D12.776.167.024.687
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Apc11 Subunit, Anaphase-Promoting Complex-Cyclosome".
Below are MeSH descriptors whose meaning is more specific than "Apc11 Subunit, Anaphase-Promoting Complex-Cyclosome".
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Year | Major Topic | Minor Topic | Total |
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2001 | 0 | 1 | 1 |
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Below are the most recent publications written about "Apc11 Subunit, Anaphase-Promoting Complex-Cyclosome" by people in Profiles.
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APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex. Mol Biol Cell. 2001 Dec; 12(12):3839-51.