Apc8 Subunit, Anaphase-Promoting Complex-Cyclosome
"Apc8 Subunit, Anaphase-Promoting Complex-Cyclosome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly conserved subunit of the anaphase-promoting complex (APC-C) containing multiple 34-amino-acid tetratricopeptide repeats. These domains, also found in Apc3, Apc6, and Apc7, have been shown to mediate protein-protein interactions, suggesting that Apc8 may assist in coordinating the juxtaposition of the catalytic and substrate recognition module subunits relative to coactivators and APC-C inhibitors.
| Descriptor ID |
D064196
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| MeSH Number(s) |
D08.811.464.938.750.092.996 D12.776.167.024.996
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Apc8 Subunit, Anaphase-Promoting Complex-Cyclosome".
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
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Below are the most recent publications written about "Apc8 Subunit, Anaphase-Promoting Complex-Cyclosome" by people in Profiles.
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Transcript map and comparative analysis of the 1.5-Mb commonly deleted segment of human 5q31 in malignant myeloid diseases with a del(5q). Genomics. 2001 Jan 15; 71(2):235-45.