Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome
"Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The largest subunit of the anaphase-promoting complex. It acts primarily as a scaffold for the proper organization and arrangement of subunits. The C-terminal region of Apc1 contains a series of tandem amino acid repeats that are also seen in the 26S proteasome regulatory particle, and may assist with forming and stabilizing protein-protein interactions.
| Descriptor ID |
D064189
|
| MeSH Number(s) |
D08.811.464.938.750.092.500 D12.776.167.024.500
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| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome".
Below are MeSH descriptors whose meaning is more specific than "Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome".
This graph shows the total number of publications written about "Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome" by people in this website by year, and whether "Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome" by people in Profiles.
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Mutation of the Apc1 homologue shattered disrupts normal eye development by disrupting G1 cell cycle arrest and progression through mitosis. Dev Biol. 2007 Sep 15; 309(2):222-35.