 Factor IX
"Factor IX" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Storage-stable blood coagulation factor acting in the intrinsic pathway. Its activated form, IXa, forms a complex with factor VIII and calcium on platelet factor 3 to activate factor X to Xa. Deficiency of factor IX results in HEMOPHILIA B (Christmas Disease).
| Descriptor ID |
D005164
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| MeSH Number(s) |
D12.776.124.125.375 D23.119.375
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| Concept/Terms |
Factor IX- Factor IX
- Christmas Factor
- Coagulation Factor IX
- Factor IX, Coagulation
- IX, Coagulation Factor
- Factor IX Fraction
- Fraction, Factor IX
- IX Fraction, Factor
- PTC
- Blood Coagulation Factor IX
- Factor IX Complex
- Complex, Factor IX
- IX Complex, Factor
- Autoprothrombin II
- Plasma Thromboplastin Component
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Below are MeSH descriptors whose meaning is more general than "Factor IX".
Below are MeSH descriptors whose meaning is more specific than "Factor IX".
This graph shows the total number of publications written about "Factor IX" by people in this website by year, and whether "Factor IX" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1990 | 1 | 0 | 1 | | 1996 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Factor IX" by people in Profiles.
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Zhao J, Xu W, Ross JW, Walters EM, Butler SP, Whyte JJ, Kelso L, Fatemi M, Vanderslice NC, Giroux K, Spate LD, Samuel MS, Murphy CN, Wells KD, Masiello NC, Prather RS, Velander WH. Engineering protein processing of the mammary gland to produce abundant hemophilia B therapy in milk. Sci Rep. 2015 Sep 21; 5:14176.
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Dobrzynski E, Fitzgerald JC, Cao O, Mingozzi F, Wang L, Herzog RW. Prevention of cytotoxic T lymphocyte responses to factor IX-expressing hepatocytes by gene transfer-induced regulatory T cells. Proc Natl Acad Sci U S A. 2006 Mar 21; 103(12):4592-7.
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Gejman PV, Cao Q, Guedj F, Sommer S. The sensitivity of denaturing gradient gel electrophoresis: a blinded analysis. Mutat Res. 1998 May; 382(3-4):109-14.
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Hortelano G, Al-Hendy A, Ofosu FA, Chang PL. Delivery of human factor IX in mice by encapsulated recombinant myoblasts: a novel approach towards allogeneic gene therapy of hemophilia B. Blood. 1996 Jun 15; 87(12):5095-103.
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Gejman PV, Detera-Wadleigh S, Martinez MM, Berrettini WH, Goldin LR, Gelernter J, Hsieh WT, Gershon ES. Manic depressive illness not linked to factor IX region in an independent series of pedigrees. Genomics. 1990 Dec; 8(4):648-55.
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