Lymphocyte Activation
"Lymphocyte Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.
Descriptor ID |
D008213
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MeSH Number(s) |
E01.370.225.812.482 E05.200.812.482 E05.478.594.530 G12.425.747 G12.450.050.400.545
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Concept/Terms |
Lymphocyte Activation- Lymphocyte Activation
- Activation, Lymphocyte
- Blastogenesis
- Lymphoblast Transformation
- Transformation, Lymphocyte
- Lymphocyte Transformation
- Transformation, Blast
- Transformation, Lymphoblast
- Blast Transformation
- Lymphocyte Stimulation
- Stimulation, Lymphocyte
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Below are MeSH descriptors whose meaning is more general than "Lymphocyte Activation".
Below are MeSH descriptors whose meaning is more specific than "Lymphocyte Activation".
This graph shows the total number of publications written about "Lymphocyte Activation" by people in this website by year, and whether "Lymphocyte Activation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1980 | 3 | 3 | 6 | 1981 | 1 | 1 | 2 | 1982 | 3 | 1 | 4 | 1983 | 2 | 1 | 3 | 1984 | 4 | 4 | 8 | 1985 | 1 | 4 | 5 | 1986 | 1 | 4 | 5 | 1987 | 1 | 6 | 7 | 1988 | 5 | 8 | 13 | 1989 | 4 | 8 | 12 | 1990 | 3 | 5 | 8 | 1991 | 4 | 6 | 10 | 1992 | 4 | 4 | 8 | 1993 | 7 | 9 | 16 | 1994 | 5 | 9 | 14 | 1995 | 4 | 13 | 17 | 1996 | 4 | 10 | 14 | 1997 | 2 | 9 | 11 | 1998 | 6 | 7 | 13 | 1999 | 8 | 16 | 24 | 2000 | 4 | 5 | 9 | 2001 | 5 | 18 | 23 | 2002 | 7 | 20 | 27 | 2003 | 6 | 14 | 20 | 2004 | 7 | 20 | 27 | 2005 | 6 | 16 | 22 | 2006 | 5 | 13 | 18 | 2007 | 2 | 17 | 19 | 2008 | 6 | 7 | 13 | 2009 | 7 | 16 | 23 | 2010 | 5 | 10 | 15 | 2011 | 2 | 11 | 13 | 2012 | 8 | 7 | 15 | 2013 | 2 | 20 | 22 | 2014 | 2 | 14 | 16 | 2015 | 4 | 12 | 16 | 2016 | 4 | 16 | 20 | 2017 | 5 | 8 | 13 | 2018 | 3 | 7 | 10 | 2019 | 4 | 6 | 10 | 2020 | 3 | 5 | 8 | 2021 | 5 | 8 | 13 | 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Lymphocyte Activation" by people in Profiles.
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Chowdhury RR, D'Addabbo J, Huang X, Veizades S, Sasagawa K, Louis DM, Cheng P, Sokol J, Jensen A, Tso A, Shankar V, Wendel BS, Bakerman I, Liang G, Koyano T, Fong R, Nau AN, Ahmad H, Gopakumar J, Wirka R, Lee AS, Boyd J, Woo YJ, Quertermous T, Gulati GS, Jaiswal S, Chien YH, Chan CKF, Davis MM, Nguyen PK. Human Coronary Plaque T Cells Are Clonal and Cross-React to Virus and Self. Circ Res. 2022 05 13; 130(10):1510-1530.
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Odunsi K, Qian F, Lugade AA, Yu H, Geller MA, Fling SP, Kaiser JC, Lacroix AM, D'Amico L, Ramchurren N, Morishima C, Disis ML, Dennis L, Danaher P, Warren S, Nguyen VA, Ravi S, Tsuji T, Rosario S, Zha W, Hutson A, Liu S, Lele S, Zsiros E, McGray AJR, Chiello J, Koya R, Chodon T, Morrison CD, Putluri V, Putluri N, Mager DE, Gunawan R, Cheever MA, Battaglia S, Matsuzaki J. Metabolic adaptation of ovarian tumors in patients treated with an IDO1 inhibitor constrains antitumor immune responses. Sci Transl Med. 2022 03 16; 14(636):eabg8402.
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Rogers D, Sood A, Wang H, van Beek JJP, Rademaker TJ, Artusa P, Schneider C, Shen C, Wong DC, Bhagrath A, Lebel M?, Condotta SA, Richer MJ, Martins AJ, Tsang JS, Barreiro LB, Fran?ois P, Langlais D, Melichar HJ, Textor J, Mandl JN. Pre-existing chromatin accessibility and gene expression differences among naive CD4+ T?cells influence effector potential. Cell Rep. 2021 11 30; 37(9):110064.
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Maulloo CD, Cao S, Watkins EA, Raczy MM, Solanki AS, Nguyen M, Reda JW, Shim HN, Wilson DS, Swartz MA, Hubbell JA. Lymph Node-Targeted Synthetically Glycosylated Antigen Leads to Antigen-Specific Immunological Tolerance. Front Immunol. 2021; 12:714842.
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Chen JA, Hou Y, Roskin KM, Arber DA, Bangs CD, Baughn LB, Cherry AM, Ewalt MD, Fire AZ, Fresard L, Kearney HM, Montgomery SB, Ohgami RS, Pearce KE, Pitel BA, Merker JD, Gotlib J. Lymphoid blast transformation in an MPN with BCR-JAK2 treated with ruxolitinib: putative mechanisms of resistance. Blood Adv. 2021 09 14; 5(17):3492-3496.
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Pachynski RK, Morishima C, Szmulewitz R, Harshman L, Appleman L, Monk P, Bitting RL, Kucuk O, Millard F, Seigne JD, Fling SP, Maecker HT, Duault C, Ramchurren N, Hess B, D'Amico L, Lacroix A, Kaiser JC, Morre M, Gr?goire A, Cheever M, Yu EY, Fong L. IL-7 expands lymphocyte populations and enhances immune responses to sipuleucel-T in patients with metastatic castration-resistant prostate cancer (mCRPC). J Immunother Cancer. 2021 08; 9(8).
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Polese B, Thurairajah B, Zhang H, Soo CL, McMahon CA, Fontes G, Hussain SNA, Abadie V, King IL. Prostaglandin E2 amplifies IL-17 production by ?d T?cells during barrier inflammation. Cell Rep. 2021 07 27; 36(4):109456.
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Das S, Marin ND, Esaulova E, Ahmed M, Swain A, Rosa BA, Mitreva M, Rangel-Moreno J, Netea MG, Barreiro LB, Divangahi M, Artyomov MN, Kaushal D, Khader SA. Lung Epithelial Signaling Mediates Early Vaccine-Induced CD4+ T Cell Activation and Mycobacterium tuberculosis Control. mBio. 2021 08 31; 12(4):e0146821.
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Wong HS, Park K, Gola A, Baptista AP, Miller CH, Deep D, Lou M, Boyd LF, Rudensky AY, Savage PA, Altan-Bonnet G, Tsang JS, Germain RN. A local regulatory T?cell feedback circuit maintains immune homeostasis by pruning self-activated T?cells. Cell. 2021 07 22; 184(15):3981-3997.e22.
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Klawon DEJ, Gilmore DC, Leonard JD, Miller CH, Chao JL, Walker MT, Duncombe RK, Tung KS, Adams EJ, Savage PA. Altered selection on a single self-ligand promotes susceptibility to organ-specific T cell infiltration. J Exp Med. 2021 06 07; 218(6).
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