 Lymphocyte Activation
"Lymphocyte Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.
| Descriptor ID |
D008213
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| MeSH Number(s) |
E01.370.225.812.482 E05.200.812.482 E05.478.594.530 G12.425.747 G12.450.050.400.545
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| Concept/Terms |
Lymphocyte Activation- Lymphocyte Activation
- Activation, Lymphocyte
- Blastogenesis
- Lymphoblast Transformation
- Transformation, Lymphocyte
- Lymphocyte Transformation
- Transformation, Blast
- Transformation, Lymphoblast
- Blast Transformation
- Lymphocyte Stimulation
- Stimulation, Lymphocyte
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Below are MeSH descriptors whose meaning is more general than "Lymphocyte Activation".
Below are MeSH descriptors whose meaning is more specific than "Lymphocyte Activation".
This graph shows the total number of publications written about "Lymphocyte Activation" by people in this website by year, and whether "Lymphocyte Activation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 3 | 4 | 7 | | 1981 | 1 | 2 | 3 | | 1982 | 3 | 2 | 5 | | 1983 | 6 | 2 | 8 | | 1984 | 9 | 4 | 13 | | 1985 | 1 | 5 | 6 | | 1986 | 4 | 5 | 9 | | 1987 | 5 | 7 | 12 | | 1988 | 7 | 9 | 16 | | 1989 | 7 | 9 | 16 | | 1990 | 4 | 6 | 10 | | 1991 | 4 | 7 | 11 | | 1992 | 4 | 4 | 8 | | 1993 | 7 | 10 | 17 | | 1994 | 6 | 11 | 17 | | 1995 | 4 | 15 | 19 | | 1996 | 4 | 10 | 14 | | 1997 | 3 | 9 | 12 | | 1998 | 6 | 8 | 14 | | 1999 | 8 | 16 | 24 | | 2000 | 5 | 4 | 9 | | 2001 | 5 | 19 | 24 | | 2002 | 7 | 19 | 26 | | 2003 | 7 | 14 | 21 | | 2004 | 7 | 18 | 25 | | 2005 | 6 | 16 | 22 | | 2006 | 5 | 13 | 18 | | 2007 | 2 | 17 | 19 | | 2008 | 6 | 7 | 13 | | 2009 | 5 | 16 | 21 | | 2010 | 4 | 8 | 12 | | 2011 | 2 | 9 | 11 | | 2012 | 8 | 5 | 13 | | 2013 | 1 | 16 | 17 | | 2014 | 1 | 13 | 14 | | 2015 | 3 | 10 | 13 | | 2016 | 5 | 14 | 19 | | 2017 | 5 | 7 | 12 | | 2018 | 3 | 5 | 8 | | 2019 | 2 | 2 | 4 | | 2020 | 2 | 0 | 2 |
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Below are the most recent publications written about "Lymphocyte Activation" by people in Profiles.
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Wu J, Hayes BW, Phoenix C, Macias GS, Miao Y, Choi HW, Hughes FM, Todd Purves J, Lee Reinhardt R, Abraham SN. A highly polarized TH2 bladder response to infection promotes epithelial repair at the expense of preventing new infections. Nat Immunol. 2020 06; 21(6):671-683.
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Fichtner AS, Karunakaran MM, Gu S, Boughter CT, Borowska MT, Starick L, Nöhren A, Göbel TW, Adams EJ, Herrmann T. Alpaca (Vicugna pacos), the first nonprimate species with a phosphoantigen-reactive V?9Vd2 T cell subset. Proc Natl Acad Sci U S A. 2020 03 24; 117(12):6697-6707.
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Wong JB, Hewitt SL, Heltemes-Harris LM, Mandal M, Johnson K, Rajewsky K, Koralov SB, Clark MR, Farrar MA, Skok JA. B-1a cells acquire their unique characteristics by bypassing the pre-BCR selection stage. Nat Commun. 2019 10 18; 10(1):4768.
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He L, Du J, Chen Y, Liu C, Zhou M, Adhikari S, Rubin DT, Pekow J, Li YC. Renin-angiotensin system promotes colonic inflammation by inducing TH17 activation via JAK2/STAT pathway. Am J Physiol Gastrointest Liver Physiol. 2019 06 01; 316(6):G774-G784.
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Guram K, Kim SS, Wu V, Sanders PD, Patel S, Schoenberger SP, Cohen EEW, Chen SY, Sharabi AB. A Threshold Model for T-Cell Activation in the Era of Checkpoint Blockade Immunotherapy. Front Immunol. 2019; 10:491.
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Moshfegh CM, Collins CW, Gunda V, Vasanthakumar A, Cao JZ, Singh PK, Godley LA, Case AJ. Mitochondrial superoxide disrupts the metabolic and epigenetic landscape of CD4+ and CD8+ T-lymphocytes. Redox Biol. 2019 10; 27:101141.
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Aue G, Sun C, Liu D, Park JH, Pittaluga S, Tian X, Lee E, Soto S, Valdez J, Maric I, Stetler-Stevenson M, Yuan C, Nakamura Y, Muranski P, Wiestner A. Activation of Th1 Immunity within the Tumor Microenvironment Is Associated with Clinical Response to Lenalidomide in Chronic Lymphocytic Leukemia. J Immunol. 2018 10 01; 201(7):1967-1974.
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Konjar Š, Frising UC, Ferreira C, Hinterleitner R, Mayassi T, Zhang Q, Blankenhaus B, Haberman N, Loo Y, Guedes J, Baptista M, Innocentin S, Stange J, Strathdee D, Jabri B, Veldhoen M. Mitochondria maintain controlled activation state of epithelial-resident T lymphocytes. Sci Immunol. 2018 06 22; 3(24).
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Tu E, Chia CPZ, Chen W, Zhang D, Park SA, Jin W, Wang D, Alegre ML, Zhang YE, Sun L, Chen W. T Cell Receptor-Regulated TGF-ß Type I Receptor Expression Determines T Cell Quiescence and Activation. Immunity. 2018 04 17; 48(4):745-759.e6.
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Gu S, Borowska MT, Boughter CT, Adams EJ. Butyrophilin3A proteins and V?9Vd2 T cell activation. Semin Cell Dev Biol. 2018 12; 84:65-74.
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