"Lymphocyte Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.
| Descriptor ID |
D008213
|
| MeSH Number(s) |
E01.370.225.812.482 E05.200.812.482 E05.478.594.530 G12.450.050.400.545 G12.565
|
| Concept/Terms |
Lymphocyte Activation- Lymphocyte Activation
- Activation, Lymphocyte
- Blast Transformation
- Blastogenesis
- Lymphocyte Stimulation
- Stimulation, Lymphocyte
- Lymphocyte Transformation
- Transformation, Lymphoblast
- Lymphoblast Transformation
- Transformation, Blast
- Transformation, Lymphocyte
|
Below are MeSH descriptors whose meaning is more general than "Lymphocyte Activation".
Below are MeSH descriptors whose meaning is more specific than "Lymphocyte Activation".
This graph shows the total number of publications written about "Lymphocyte Activation" by people in this website by year, and whether "Lymphocyte Activation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 5 | 8 | 13 |
| 1995 | 4 | 12 | 16 |
| 1996 | 4 | 9 | 13 |
| 1997 | 2 | 9 | 11 |
| 1998 | 6 | 7 | 13 |
| 1999 | 7 | 16 | 23 |
| 2000 | 4 | 5 | 9 |
| 2001 | 5 | 17 | 22 |
| 2002 | 7 | 19 | 26 |
| 2003 | 6 | 12 | 18 |
| 2004 | 7 | 18 | 25 |
| 2005 | 5 | 14 | 19 |
| 2006 | 5 | 12 | 17 |
| 2007 | 2 | 16 | 18 |
| 2008 | 6 | 7 | 13 |
| 2009 | 7 | 18 | 25 |
| 2010 | 5 | 9 | 14 |
| 2011 | 1 | 11 | 12 |
| 2012 | 7 | 7 | 14 |
| 2013 | 2 | 20 | 22 |
| 2014 | 2 | 13 | 15 |
| 2015 | 4 | 13 | 17 |
| 2016 | 4 | 16 | 20 |
| 2017 | 5 | 11 | 16 |
| 2018 | 3 | 11 | 14 |
| 2019 | 4 | 6 | 10 |
| 2020 | 4 | 6 | 10 |
| 2021 | 6 | 11 | 17 |
| 2022 | 0 | 2 | 2 |
| 2023 | 0 | 3 | 3 |
| 2024 | 2 | 5 | 7 |
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Below are the most recent publications written about "Lymphocyte Activation" by people in Profiles.
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NK Receptor Signaling Lowers TCR Activation Threshold, Enhancing Selective Recognition of Cancer Cells by TAA-Specific CTLs. Cancer Immunol Res. 2024 Oct 01; 12(10):1421-1437.
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Ligand-induced segregation from large cell-surface phosphatases is a critical step in ?d TCR triggering. Cell Rep. 2024 Sep 24; 43(9):114761.
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Androgens contribute to sex bias of autoimmunity in mice by T cell-intrinsic regulation of Ptpn22 phosphatase expression. Nat Commun. 2024 Sep 03; 15(1):7688.
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Upregulated selenoprotein I during lipopolysaccharide-induced B cell activation promotes lipidomic changes and is required for effective differentiation into IgM-secreting plasma B cells. J Leukoc Biol. 2024 Jun 28; 116(1):6-17.
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Immunotherapy-activated T cells recruit and skew late-stage activated M1-like macrophages that are critical for therapeutic efficacy. Cancer Cell. 2024 Jun 10; 42(6):1032-1050.e10.
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Cysteine-binding adjuvant enhances survival and promotes immune function in a murine model of acute myeloid leukemia. Blood Adv. 2024 04 09; 8(7):1747-1759.
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Delivery of loaded MR1 monomer results in efficient ligand exchange to host MR1 and subsequent MR1T cell activation. Commun Biol. 2024 02 24; 7(1):228.
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Base-editing mutagenesis maps alleles to tune human T cell functions. Nature. 2024 Jan; 625(7996):805-812.
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Metabolic modulation of mitochondrial mass during CD4+ TÂ cell activation. Cell Chem Biol. 2023 09 21; 30(9):1064-1075.e8.
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MHC class II antigen presentation by intestinal epithelial cells fine-tunes bacteria-reactive CD4 T-cell responses. Mucosal Immunol. 2024 Jun; 17(3):416-430.