 Lymphocyte Activation
"Lymphocyte Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.
| Descriptor ID |
D008213
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| MeSH Number(s) |
E01.370.225.812.482 E05.200.812.482 E05.478.594.530 G12.425.747 G12.450.050.400.545
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| Concept/Terms |
Lymphocyte Activation- Lymphocyte Activation
- Activation, Lymphocyte
- Blastogenesis
- Lymphoblast Transformation
- Transformation, Lymphocyte
- Lymphocyte Transformation
- Transformation, Blast
- Transformation, Lymphoblast
- Blast Transformation
- Lymphocyte Stimulation
- Stimulation, Lymphocyte
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Below are MeSH descriptors whose meaning is more general than "Lymphocyte Activation".
Below are MeSH descriptors whose meaning is more specific than "Lymphocyte Activation".
This graph shows the total number of publications written about "Lymphocyte Activation" by people in this website by year, and whether "Lymphocyte Activation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 3 | 4 | 7 | | 1981 | 1 | 2 | 3 | | 1982 | 3 | 2 | 5 | | 1983 | 6 | 2 | 8 | | 1984 | 9 | 4 | 13 | | 1985 | 1 | 5 | 6 | | 1986 | 4 | 5 | 9 | | 1987 | 5 | 7 | 12 | | 1988 | 8 | 9 | 17 | | 1989 | 7 | 9 | 16 | | 1990 | 4 | 6 | 10 | | 1991 | 4 | 7 | 11 | | 1992 | 4 | 4 | 8 | | 1993 | 7 | 10 | 17 | | 1994 | 6 | 11 | 17 | | 1995 | 4 | 15 | 19 | | 1996 | 4 | 10 | 14 | | 1997 | 3 | 9 | 12 | | 1998 | 6 | 8 | 14 | | 1999 | 8 | 16 | 24 | | 2000 | 5 | 4 | 9 | | 2001 | 5 | 19 | 24 | | 2002 | 7 | 20 | 27 | | 2003 | 7 | 14 | 21 | | 2004 | 7 | 20 | 27 | | 2005 | 6 | 16 | 22 | | 2006 | 5 | 14 | 19 | | 2007 | 2 | 17 | 19 | | 2008 | 6 | 7 | 13 | | 2009 | 6 | 17 | 23 | | 2010 | 4 | 10 | 14 | | 2011 | 2 | 9 | 11 | | 2012 | 8 | 8 | 16 | | 2013 | 2 | 17 | 19 | | 2014 | 1 | 13 | 14 | | 2015 | 3 | 12 | 15 | | 2016 | 5 | 14 | 19 | | 2017 | 5 | 7 | 12 | | 2018 | 3 | 6 | 9 | | 2019 | 3 | 6 | 9 | | 2020 | 3 | 5 | 8 | | 2021 | 2 | 4 | 6 |
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Below are the most recent publications written about "Lymphocyte Activation" by people in Profiles.
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Klawon DEJ, Gilmore DC, Leonard JD, Miller CH, Chao JL, Walker MT, Duncombe RK, Tung KS, Adams EJ, Savage PA. Altered selection on a single self-ligand promotes susceptibility to organ-specific T cell infiltration. J Exp Med. 2021 06 07; 218(6).
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Guthmiller JJ, Utset HA, Wilson PC. B Cell Responses against Influenza Viruses: Short-Lived Humoral Immunity against a Life-Long Threat. Viruses. 2021 05 22; 13(6).
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Shi M, Willing SE, Kim HK, Schneewind O, Missiakas D. Peptidoglycan Contribution to the B Cell Superantigen Activity of Staphylococcal Protein A. mBio. 2021 04 20; 12(2).
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Quandt J, Arnovitz S, Haghi L, Woehlk J, Mohsin A, Okoreeh M, Mathur PS, Emmanuel AO, Osman A, Krishnan M, Morin SB, Pearson AT, Sweis RF, Pekow J, Weber CR, Khazaie K, Gounari F. Wnt-ß-catenin activation epigenetically reprograms Treg cells in inflammatory bowel disease and dysplastic progression. Nat Immunol. 2021 04; 22(4):471-484.
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Surette FA, Guthmiller JJ, Li L, Sturtz AJ, Vijay R, Pope RL, McClellan BL, Pack AD, Zander RA, Shao P, Lan LY, Fernandez-Ruiz D, Heath WR, Wilson PC, Butler NS. Extrafollicular CD4 T cell-derived IL-10 functions rapidly and transiently to support anti-Plasmodium humoral immunity. PLoS Pathog. 2021 02; 17(2):e1009288.
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Liu S, Galat V, Galat Y, Lee YKA, Wainwright D, Wu J. NK cell-based cancer immunotherapy: from basic biology to clinical development. J Hematol Oncol. 2021 01 06; 14(1):7.
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El Bissati K, Zhou Y, Paulillo SM, Raman SK, Karch CP, Reed S, Estes A, Estes A, Lykins J, Burkhard P, McLeod R. Engineering and characterization of a novel Self Assembling Protein for Toxoplasma peptide vaccine in HLA-A*11:01, HLA-A*02:01 and HLA-B*07:02 transgenic mice. Sci Rep. 2020 10 12; 10(1):16984.
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Gioulbasani M, Galaras A, Grammenoudi S, Moulos P, Dent AL, Sigvardsson M, Hatzis P, Kee BL, Verykokakis M. The transcription factor BCL-6 controls early development of innate-like T cells. Nat Immunol. 2020 09; 21(9):1058-1069.
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Wu J, Hayes BW, Phoenix C, Macias GS, Miao Y, Choi HW, Hughes FM, Todd Purves J, Lee Reinhardt R, Abraham SN. A highly polarized TH2 bladder response to infection promotes epithelial repair at the expense of preventing new infections. Nat Immunol. 2020 06; 21(6):671-683.
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Kim SS, Shen S, Miyauchi S, Sanders PD, Franiak-Pietryga I, Mell L, Gutkind JS, Cohen EEW, Califano JA, Sharabi AB. B Cells Improve Overall Survival in HPV-Associated Squamous Cell Carcinomas and Are Activated by Radiation and PD-1 Blockade. Clin Cancer Res. 2020 07 01; 26(13):3345-3359.
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