 Interleukin-5
"Interleukin-5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine that promotes differentiation and activation of EOSINOPHILS. It also triggers activated B-LYMPHOCYTES to differentiate into IMMUNOGLOBULIN-secreting cells.
| Descriptor ID |
D015848
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| MeSH Number(s) |
D12.644.276.374.465.505 D12.776.467.374.465.505 D23.529.374.465.505
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| Concept/Terms |
Interleukin-5- Interleukin-5
- Interleukin 5
- BCGF-II
- Differentiation Factor, Eosinophil
- Eosinophil Differentiation Factor
- IL5
- T-Cell Replacing Factor
- Replacing Factor, T-Cell
- T-Cell-Replacing Factor
- T Cell Replacing Factor
- B-Cell Growth Factor-II
- B Cell Growth Factor II
- IL-5
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Below are MeSH descriptors whose meaning is more general than "Interleukin-5".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-5".
This graph shows the total number of publications written about "Interleukin-5" by people in this website by year, and whether "Interleukin-5" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1984 | 0 | 1 | 1 | | 1989 | 0 | 1 | 1 | | 1992 | 1 | 0 | 1 | | 1993 | 0 | 2 | 2 | | 1995 | 0 | 2 | 2 | | 1996 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 1999 | 0 | 2 | 2 | | 2000 | 0 | 1 | 1 | | 2002 | 1 | 1 | 2 | | 2003 | 0 | 2 | 2 | | 2004 | 1 | 1 | 2 | | 2005 | 1 | 0 | 1 | | 2007 | 0 | 2 | 2 | | 2008 | 0 | 1 | 1 | | 2011 | 0 | 2 | 2 | | 2017 | 1 | 2 | 3 | | 2019 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Interleukin-5" by people in Profiles.
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Krishack PA, Louviere TJ, Decker TS, Kuzel TG, Greenberg JA, Camacho DF, Hrusch CL, Sperling AI, Verhoef PA. Protection against Staphylococcus aureus bacteremia-induced mortality depends on ILC2s and eosinophils. JCI Insight. 2019 03 21; 4(6).
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Kallur L, Gonzalez-Estrada A, Eidelman F, Dimov V. Pharmacokinetic drug evaluation of mepolizumab for the treatment of severe asthma associated with persistent eosinophilic inflammation in adults. Expert Opin Drug Metab Toxicol. 2017 Dec; 13(12):1275-1280.
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Hrusch CL, Manns ST, Bryazka D, Casaos J, Bonham CA, Jaffery MR, Blaine KM, Mills KAM, Verhoef PA, Adegunsoye AO, Williams JW, Tjota MY, Moore TV, Strek ME, Noth I, Sperling AI. ICOS protects against mortality from acute lung injury through activation of IL-5+ ILC2s. Mucosal Immunol. 2018 01; 11(1):61-70.
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Willson TJ, Naclerio RM, Lee SE. Monoclonal Antibodies for the Treatment of Nasal Polyps. Immunol Allergy Clin North Am. 2017 05; 37(2):357-367.
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Kolokythas A, Karas M, Sarna T, Flick W, Miloro M. Does cytokine profiling of aspirate from jaw cysts and tumors have a role in diagnosis? J Oral Maxillofac Surg. 2012 May; 70(5):1070-80.
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Zhu M, Liu PY, Kasahara DI, Williams AS, Verbout NG, Halayko AJ, Fedulov A, Shoji T, Williams ES, Noma K, Shore SA, Liao JK. Role of Rho kinase isoforms in murine allergic airway responses. Eur Respir J. 2011 Oct; 38(4):841-50.
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Cannon JL, Collins A, Mody PD, Balachandran D, Henriksen KJ, Smith CE, Tong J, Clay BS, Miller SD, Sperling AI. CD43 regulates Th2 differentiation and inflammation. J Immunol. 2008 Jun 01; 180(11):7385-93.
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Meliton AY, Munoz NM, Zhu X, Leff AR. Attenuated translocation of group IVa phospholipase A2 and up-regulated annexin-1 synthesis by glucocorticoid blocks beta 2-integrin adhesion in neutrophils. J Leukoc Biol. 2008 Feb; 83(2):344-51.
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Meliton AY, Munoz NM, Leff AR. Blockade of avidity and focal clustering of beta 2-integrin by cysteinyl leukotriene antagonism attenuates eosinophil adhesion. J Allergy Clin Immunol. 2007 Dec; 120(6):1316-23.
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Sano M, Leff AR, Myou S, Boetticher E, Meliton AY, Learoyd J, Lambertino AT, Munoz NM, Zhu X. Regulation of interleukin-5-induced beta2-integrin adhesion of human eosinophils by phosphoinositide 3-kinase. Am J Respir Cell Mol Biol. 2005 Jul; 33(1):65-70.
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